Popovic Kosta, McKisson Jack E, Kross Brian, Lee Seungjoon, McKisson John, Weisenberger Andrew G, Proffitt James, Stolin Alexander, Majewski Stan, Williams Mark B
Department of Physics, University of Virginia, Charlottesville, VA 22904 USA. He is now with the Department of Physics and Optical Engineering, Rose-Hulman Institute of Technology, Terre Haute, IN 47807 USA.
Radiation Detector & Imaging Group in Thomas Jefferson National Accelerator Facility, Newport News, VA, 23606 USA.
IEEE Trans Nucl Sci. 2014 May;61(3):1084-1091. doi: 10.1109/TNS.2014.2308284. Epub 2014 May 20.
This paper describes the development of a hand-held gamma camera for intraoperative surgical guidance that is based on silicon photomultiplier (SiPM) technology. The camera incorporates a cerium doped lanthanum bromide (LaBr:Ce) plate scintillator, an array of 80 SiPM photodetectors and a two-layer parallel-hole collimator. The field of view is circular with a 60 mm diameter. The disk-shaped camera housing is 75 mm in diameter, approximately 40.5 mm thick and has a mass of only 1.4 kg, permitting either hand-held or arm-mounted use. All camera components are integrated on a mobile cart that allows easy transport. The camera was developed for use in surgical procedures including determination of the location and extent of primary carcinomas, detection of secondary lesions and sentinel lymph node biopsy (SLNB). Here we describe the camera design and its principal operating characteristics, including spatial resolution, energy resolution, sensitivity uniformity, and geometric linearity. The gamma camera has an intrinsic spatial resolution of 4.2 mm FWHM, an energy resolution of 21.1 % FWHM at 140 keV, and a sensitivity of 481 and 73 cps/MBq when using the single- and double-layer collimators, respectively.
本文描述了一种基于硅光电倍增管（SiPM）技术的用于术中手术引导的手持式γ相机的开发。该相机集成了铈掺杂溴化镧（LaBr:Ce）平板闪烁体、80个SiPM光电探测器阵列和双层平行孔准直器。视野为直径60 mm的圆形。圆盘形相机外壳直径75 mm，厚约40.5 mm，质量仅1.4 kg，既可以手持使用，也可以安装在手臂上使用。相机的所有组件都集成在一个移动推车上，便于运输。该相机是为外科手术而开发的，包括确定原发性癌的位置和范围、检测继发性病变以及前哨淋巴结活检（SLNB）。在此，我们描述相机的设计及其主要操作特性，包括空间分辨率、能量分辨率、灵敏度均匀性和几何线性度。该γ相机的固有空间分辨率为4.2 mm半高宽，在140 keV时能量分辨率为21.1 %半高宽，使用单层和双层准直器时的灵敏度分别为481和73 cps/MBq。
