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幼年特发性关节炎患儿的经验性分类:疼痛与健康的多维度方法。

Empirical classification of children with JIA: a multidimensional approach to pain and well-being.

作者信息

Vuorimaa H, Tamm K, Honkanen V, Konttinen Y T, Komulainen E, Santavirta N

机构信息

Department of Rheumatology, Rheumatism Foundation Hospital, Heinola, Finland.

出版信息

Clin Exp Rheumatol. 2008 Sep-Oct;26(5):954-61.

Abstract

OBJECTIVE

To investigate the relationship between children's arthritis self-efficacy, trait-anxiety, depression, clinical state of the disease (pain, disability, number of somatic complaints and active joints) and age of the child.

METHODS

Trait anxiety and depression of JIA patients were measured by standardized scales (STAIC and CDI). For assessing self-efficacy CASE-scale was used. Pain, CHAQ and active joint count were used as indicators of the disease severity. The K-means cluster procedure was used to classify 145 consecutively recruited patients aged 8 to 15, regarding age, trait-anxiety and depression. One-way multivariate analysis of variance (MANOVA) followed by separate ANOVA's was used for comparisons between the cluster groups. Associations between the cluster groups and the children's self-efficacy were then evaluated using multivariate analysis of variance (MANOVA).

RESULTS

Four cluster groups were identified based on the degree of depression and trait-anxiety. Clinical disease-related parameters differed significantly in the cluster groups. Pain was not necessarily related to the severity of the disease or to the diagnosis (oligoarthritis, oligoextended and polyarthritis). A higher level of self-efficacy was related to lower levels of depression, trait anxiety and pain.

CONCLUSION

In JIA, the clinical classification of disease activity and severity did not directly correspond with depression and trait-anxiety in children with JIA. Instead, these were regulated by a self-efficacy, which was associated with less pain and somatic complaints.

摘要

目的

探讨儿童关节炎自我效能感、特质焦虑、抑郁、疾病临床状态(疼痛、残疾、躯体主诉数量和活动关节数)与儿童年龄之间的关系。

方法

采用标准化量表(STAIC和CDI)测量幼年特发性关节炎(JIA)患者的特质焦虑和抑郁。使用CASE量表评估自我效能感。疼痛、儿童健康评估问卷(CHAQ)和活动关节计数用作疾病严重程度的指标。采用K均值聚类程序,根据年龄、特质焦虑和抑郁对145例连续招募的8至15岁患者进行分类。采用单因素多变量方差分析(MANOVA),随后进行单独的方差分析,以比较聚类组之间的差异。然后使用多变量方差分析(MANOVA)评估聚类组与儿童自我效能感之间的关联。

结果

根据抑郁程度和特质焦虑确定了四个聚类组。聚类组中与临床疾病相关的参数有显著差异。疼痛不一定与疾病严重程度或诊断(少关节炎、少关节炎扩展型和多关节炎)相关。较高水平的自我效能感与较低水平的抑郁、特质焦虑和疼痛相关。

结论

在幼年特发性关节炎中,疾病活动度和严重程度的临床分类与幼年特发性关节炎患儿的抑郁和特质焦虑并不直接对应。相反,这些受自我效能感的调节,自我效能感与较少的疼痛和躯体主诉相关。

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