Kaira Kyoichi, Ishizuka Tamotsu, Yanagitani Noriko, Sunaga Noriaki, Hisada Takeshi, Mori Masatomo
Department of Medicine and Molecular Science, Gunma University Graduate School of Medicine, Gunma, Japan.
Clin Nucl Med. 2008 Dec;33(12):878-9. doi: 10.1097/RLU.0b013e31818bf2f5.
Fluorodeoxyglucose positron emission tomography (FDG PET) has been widely used in the assessment of malignancy. However, FDG is not tumor-specific and may be taken up by nonmalignant conditions such as sarcoidosis. Sarcoidosis is a systemic disease and extrapulmonary lesions are also present. However, laryngeal sarcoidosis is a rare manifestation of extrapulmonary sarcoidosis. A 60-year-old man with a history of previous sarcoidosis presented with hoarseness. PET imaging demonstrated increased FDG uptake in the larynx. The histologic examination revealed laryngeal sarcoidosis. We report a case of laryngeal sarcoidosis and emphasize the role of FDG PET.
氟脱氧葡萄糖正电子发射断层扫描(FDG PET)已广泛应用于恶性肿瘤的评估。然而,FDG并非肿瘤特异性的,可能会被结节病等非恶性疾病摄取。结节病是一种全身性疾病,也会出现肺外病变。然而,喉结节病是肺外结节病的一种罕见表现。一名有结节病病史的60岁男性因声音嘶哑就诊。PET成像显示喉部FDG摄取增加。组织学检查显示为喉结节病。我们报告一例喉结节病病例,并强调FDG PET的作用。