Department of Radiology, National Center of Neurology and Psychiatry, Tokyo, Japan.
Clin Nucl Med. 2013 Feb;38(2):128-30. doi: 10.1097/RLU.0b013e318266cb25.
A 65-year-old woman with a complete atrioventricular block was diagnosed as having cardiac sarcoidosis. (18)F-FDG PET/CT imaging without unfractionated heparin loading revealed systemic abnormal uptake indicating sarcoidosis. However, the cardiac lesions were vague because of the physiological FDG uptake. One month later, (18)F-FDG PET/CT using heparin loading was performed to evaluate the lesion activity prior to the start of steroid administration. (18)F-FDG PET/CT imaging with heparin loading showed the cardiac lesions more clearly and suppressed the FDG uptake in normal myocardium. Heparin loading during FDG PET/CT may be useful for detecting cardiac involvement in patients with cardiac sarcoidosis.
一位 65 岁女性因完全性房室传导阻滞被诊断为心脏结节病。（18）F-FDG PET/CT 显像未负荷肝素时发现全身摄取异常，提示结节病。然而，由于生理 FDG 摄取，心脏病变较为模糊。一个月后，行肝素负荷（18）F-FDG PET/CT 检查以评估激素治疗前的病灶活性。肝素负荷（18）F-FDG PET/CT 显像更清楚地显示了心脏病变，并抑制了正常心肌的 FDG 摄取。FDG PET/CT 时负荷肝素可能有助于检测心脏结节病患者的心脏受累。
