Bhargava Peeyush, Hanif Muzammil, Nash Carey
Department of Nuclear Medicine and Radiology, Michael E DeBakey VA Medical Center, Houston, Texas, USA.
Clin Nucl Med. 2008 Dec;33(12):894-5. doi: 10.1097/RLU.0b013e31818ca43c.
A 59-year-old male with metastatic renal cell cancer presented with pain in the right heel. Radiographs showed a large lytic lesion in the right calcaneus, suspicious for bone metastasis. For a comprehensive morphologic and scintigraphic evaluation, a whole-body F-18 sodium fluoride (NaF) PET-CT was acquired. All lytic lesions seen on the CT showed intense peripheral fluoride uptake. Five fluoride avid lesions were not seen on the CT scan. Eight foci of mild to moderate fluoride activity were identified as degenerative joint disease on the CT scan. Intense peripheral NaF uptake was seen in the lytic lesion in the right calcaneus, which was later proven by needle biopsy to be metastasis from renal cell cancer.
一名59岁的转移性肾细胞癌男性患者出现右足跟疼痛。X线片显示右跟骨有一个大的溶骨性病变，怀疑为骨转移。为了进行全面的形态学和闪烁显像评估，进行了全身F-18氟化钠（NaF）PET-CT检查。CT上所见的所有溶骨性病变均显示周边有强烈的氟摄取。CT扫描未发现五个氟摄取活跃的病变。CT扫描将八个轻度至中度氟活性灶确定为退行性关节病。右跟骨溶骨性病变处可见强烈的周边NaF摄取，后来经针吸活检证实为肾细胞癌转移。
