Song Jin-Qiu, Zhang Jian, Yin Ming-Di, Wu Bin, Shan Shao-Yin, Duan Zhi-Quan, Xin Shi-Jie
Department of Vascular Surgery, First Affiliated Hospital of China Medical University, Shenyang 110001, China.
Zhonghua Yi Xue Za Zhi. 2008 Jun 17;88(23):1613-7.
To investigate the clinico-epidemiology features of infrarenal abdominal aortic aneurysm (AAA) and relevant prognostic factors.
The clinical records of 375 infrarenal AAA patients, 282 males and 93 females, aged (62 +/- 15), hospitalized 1988 -2007 were analyzed.
In recent ten years, the number of patients admitted because of AAA was 186.6% as high as that in the last 10 years. The rupture rate of the male AAA patients was 14.4%, significantly higher than that of the female AAA patients (6.5%, P < 0.05). The rupture rate of the AAA aged patients > or = 65 was 3.6%, significantly lower than that of the AAA patients < 65 (17.7%, P < 0.01). The aneurysm diameter of the patients with hyperextension was (6.1 +/- 3.3) cm, significantly lower than that of the patients without hypertension [(6.8 +/- 2.3) cm. P < 0.05]. The general 5-year survival rate was 70.1%. The 5-year survival rates of the female patients, patients > or = 65, without hypertension, and without coronary heart disease were, all significantly higher than those of the male patients, patients < 65, and patients with hypertension or coronary heart disease (all P < 0.05). Cox regression analysis showed that sex, smoking, and hypertension were all prognostic factors (all P < 0.05).
The morbidity of AAA increases fiercely. The AAA patients being male, smoking, or with hypertension have poorer prognosis, and age and operation method are not related to prognoses.
探讨肾下腹主动脉瘤（AAA）的临床流行病学特征及相关预后因素。
分析1988 - 2007年住院的375例肾下腹主动脉瘤患者的临床记录，其中男性282例，女性93例，年龄（62±15）岁。
近十年因AAA入院的患者数量是过去十年的186.6%。男性AAA患者的破裂率为14.4%，显著高于女性AAA患者（6.5%，P<0.05）。年龄≥65岁的AAA患者破裂率为3.6%，显著低于<65岁的AAA患者（17.7%，P<0.01）。高血压患者的动脉瘤直径为（6.1±3.3）cm，显著低于无高血压患者[（6.8±2.3）cm，P<0.05]。总体5年生存率为70.1%。女性患者、年龄≥65岁患者、无高血压患者及无冠心病患者的5年生存率均显著高于男性患者、<65岁患者及有高血压或冠心病患者（均P<0.05）。Cox回归分析显示，性别、吸烟和高血压均为预后因素（均P<0.05）。
AAA发病率急剧上升。男性、吸烟或患有高血压的AAA患者预后较差，年龄和手术方式与预后无关。
