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[肾下腹主动脉瘤的临床流行病学特征及相关预后因素]

[Clinico-epidemiological features of infrarenal abdominal aortic aneurysm and relevant prognostic factors].

作者信息

Song Jin-Qiu, Zhang Jian, Yin Ming-Di, Wu Bin, Shan Shao-Yin, Duan Zhi-Quan, Xin Shi-Jie

机构信息

Department of Vascular Surgery, First Affiliated Hospital of China Medical University, Shenyang 110001, China.

出版信息

Zhonghua Yi Xue Za Zhi. 2008 Jun 17;88(23):1613-7.

Abstract

OBJECTIVE

To investigate the clinico-epidemiology features of infrarenal abdominal aortic aneurysm (AAA) and relevant prognostic factors.

METHODS

The clinical records of 375 infrarenal AAA patients, 282 males and 93 females, aged (62 +/- 15), hospitalized 1988 -2007 were analyzed.

RESULTS

In recent ten years, the number of patients admitted because of AAA was 186.6% as high as that in the last 10 years. The rupture rate of the male AAA patients was 14.4%, significantly higher than that of the female AAA patients (6.5%, P < 0.05). The rupture rate of the AAA aged patients > or = 65 was 3.6%, significantly lower than that of the AAA patients < 65 (17.7%, P < 0.01). The aneurysm diameter of the patients with hyperextension was (6.1 +/- 3.3) cm, significantly lower than that of the patients without hypertension [(6.8 +/- 2.3) cm. P < 0.05]. The general 5-year survival rate was 70.1%. The 5-year survival rates of the female patients, patients > or = 65, without hypertension, and without coronary heart disease were, all significantly higher than those of the male patients, patients < 65, and patients with hypertension or coronary heart disease (all P < 0.05). Cox regression analysis showed that sex, smoking, and hypertension were all prognostic factors (all P < 0.05).

CONCLUSION

The morbidity of AAA increases fiercely. The AAA patients being male, smoking, or with hypertension have poorer prognosis, and age and operation method are not related to prognoses.

摘要

目的

探讨肾下腹主动脉瘤(AAA)的临床流行病学特征及相关预后因素。

方法

分析1988 - 2007年住院的375例肾下腹主动脉瘤患者的临床记录,其中男性282例,女性93例,年龄(62±15)岁。

结果

近十年因AAA入院的患者数量是过去十年的186.6%。男性AAA患者的破裂率为14.4%,显著高于女性AAA患者(6.5%,P<0.05)。年龄≥65岁的AAA患者破裂率为3.6%,显著低于<65岁的AAA患者(17.7%,P<0.01)。高血压患者的动脉瘤直径为(6.1±3.3)cm,显著低于无高血压患者[(6.8±2.3)cm,P<0.05]。总体5年生存率为70.1%。女性患者、年龄≥65岁患者、无高血压患者及无冠心病患者的5年生存率均显著高于男性患者、<65岁患者及有高血压或冠心病患者(均P<0.05)。Cox回归分析显示,性别、吸烟和高血压均为预后因素(均P<0.05)。

结论

AAA发病率急剧上升。男性、吸烟或患有高血压的AAA患者预后较差,年龄和手术方式与预后无关。

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