Ma Chun-guang, Ye Ding-wei, Li Chang-ling, Zhou Fang-jian, Yao Xu-dong, Zhang Shi-lin, Dai Bo, Zhang Hai-liang, Zhu Yao, Shen Yi-jun
Department of Oncology, Shanghai Medical College, Shanghai 200032, China.
Zhonghua Wai Ke Za Zhi. 2008 Jun 15;46(12):921-5.
To analyze the epidemiology information of prostate cancer from three centers of Beijing, Shanghai, Guangzhou, and to reflect the current situation of prostate cancer in China, and to analyze the information of 272 patients with advanced prostate cancer who received hormonal therapy to find the prognostic factors of hormone therapy.
Collect the information of 525 patients with prostate cancer from three centers. Two hundred and seventy-two cases of advanced prostate cancer with full information were selected from the 525 cases to analyze the prognostic factors of hormone therapy.
Three hundred and fifty-seven cases (68.0%) had advanced disease at diagnosis and 80.2% patients received hormone therapy as the main therapy. Prognostic analysis indicated that Gleason score, bone metastasis and prostate specific antigen nadir were independent prognostic factors of progression-free survival time.
In this report, most patients are advanced prostate cancer at diagnose, and hormonal therapy is the main therapy. Gleason score, bone metastasis, prostate specific antigen nadir are independent prognostic factors of advanced prostate cancer after hormone therapy.
分析北京、上海、广州三个中心的前列腺癌流行病学信息，反映中国前列腺癌的现状，并分析272例接受激素治疗的晚期前列腺癌患者的信息，以寻找激素治疗的预后因素。
收集三个中心525例前列腺癌患者的信息。从525例患者中选取272例信息完整的晚期前列腺癌患者，分析激素治疗的预后因素。
357例（68.0%）患者诊断时为晚期疾病，80.2%的患者接受激素治疗作为主要治疗方法。预后分析表明， Gleason评分、骨转移和前列腺特异性抗原最低点是无进展生存时间的独立预后因素。
本报告中，大多数患者诊断时为晚期前列腺癌，激素治疗是主要治疗方法。Gleason评分、骨转移、前列腺特异性抗原最低点是激素治疗后晚期前列腺癌的独立预后因素。
