Ageberg Eva, Thomeé Roland, Neeter Camille, Silbernagel Karin Grävare, Roos Ewa M
Clinical Sciences Lund, Lund University, Lund, Sweden.
Arthritis Rheum. 2008 Dec 15;59(12):1773-9. doi: 10.1002/art.24066.
To study muscle strength and functional performance in patients with anterior cruciate ligament (ACL) injury with or without surgical reconstruction 2 to 5 years after injury. Good muscle function is important in preventing early-onset osteoarthritis (OA), but the role of reconstructive surgery in restoring muscle function is unclear.
Of 121 patients with ACL injury included in a randomized controlled trial on training and surgical reconstruction versus training only (the Knee, Anterior cruciate ligament, NON-surgical versus surgical treatment [KANON] study, ISRCTN: 84752559), 54 (mean age at followup 30 years, range 20-39, 28% women) were assessed a mean +/- SD of 3 +/- 0.9 years after injury with reliable, valid, and responsive test batteries for strength (knee extension, knee flexion, leg press) and hop performance (vertical jump, one-leg hop, side hop). The Limb Symmetry Index (LSI; injured leg divided by uninjured and multiplied by 100) value and absolute values were used for comparisons between groups (analysis of variance). An LSI >or=90% was considered normal.
There were no differences between the surgical and nonsurgical treatment groups in muscle strength or functional performance. Between 44% and 89% of subjects had normal muscle function in the single tests, and between 44% and 56% had normal function in the test batteries.
The lack of differences between patients treated with training and surgical reconstruction or training only indicates that reconstructive surgery is not a prerequisite for restoring muscle function. Abnormal muscle function, found in approximately one-third or more of the patients, may be a predictor of future knee OA.
研究前交叉韧带(ACL)损伤患者在损伤后2至5年接受或未接受手术重建时的肌肉力量和功能表现。良好的肌肉功能对于预防早发性骨关节炎(OA)很重要,但重建手术在恢复肌肉功能中的作用尚不清楚。
在一项关于训练与手术重建对比单纯训练的随机对照试验(膝关节、前交叉韧带、非手术与手术治疗[KANON]研究,国际标准随机对照试验编号:84752559)中纳入的121例ACL损伤患者中,54例(随访时平均年龄30岁,范围20 - 39岁,女性占28%)在损伤后平均3±0.9年接受了评估,使用了可靠、有效且反应灵敏的测试组合来评估力量(膝关节伸展、膝关节屈曲、腿举)和跳跃表现(垂直跳跃、单腿跳跃、侧向跳跃)。采用肢体对称指数(LSI;患侧腿除以未患侧腿再乘以100)值和绝对值进行组间比较(方差分析)。LSI≥90%被认为是正常的。
手术治疗组和非手术治疗组在肌肉力量或功能表现方面没有差异。在单项测试中,44%至89%的受试者肌肉功能正常,在测试组合中,44%至56%的受试者功能正常。
接受训练与手术重建治疗的患者和仅接受训练的患者之间没有差异,这表明重建手术不是恢复肌肉功能的先决条件。约三分之一或更多患者存在的肌肉功能异常可能是未来膝关节OA的一个预测指标。