[γ射线辐照血清白蛋白的生物活性]
[Biological activity of gamma-irradiated serum albumin].
作者信息
Kopylov V A, Revin A F, Iurov S S, Shchelkaeva N V, Kuzin A M
出版信息
Radiobiologiia. 1991 Mar-Apr;31(2):216-21.
PMID:1903548
Abstract
Gamma-irradiated serum albumin activated L-tyrosine oxidation to 3,4-dioxyphenyl alanine (DOPA) and forms adducts with DOPA oxidation products. These adducts are more resistant to proteolysis and have bactericidal and mutagenic capacity. A possible role of such adducts in a radiation damage to the organism is discussed.
摘要
γ射线辐照的血清白蛋白将L-酪氨酸氧化为3,4-二羟基苯丙氨酸（多巴），并与多巴氧化产物形成加合物。这些加合物对蛋白水解更具抗性，且具有杀菌和诱变能力。本文讨论了此类加合物在生物体辐射损伤中可能发挥的作用。
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