Sadeghpour Anita, Saadatifar Hakimeh, Kiavar Majid, Esmaeilzadeh Maryam, Maleki Majid, Ojaghi Zahra, Noohi Fereidoon, Samiei Niloofar, Mohebbi Ahmad
Echocardiography Laboratory, Department of Cardiovascular Medicine, Shahid Rajaie Cardiovascular Medical Center, Tehran, Iran.
Congenit Heart Dis. 2008 Nov-Dec;3(6):415-21. doi: 10.1111/j.1747-0803.2008.00223.x.
Few reports have been published on the Doppler-derived echocardiographic data for pulmonary valve prostheses (PVPs). The aim of this study was to provide a comprehensive Doppler echocardiographic assessment of PVPs.
We studied 40 patients (mean age 24.2) with PVPs: 13 (32.5%) mechanical and 27 (67.5%) bioprosthetic valves. After clinical evaluation, all patients underwent complete, two-dimensional and Doppler studies.
In 30 patients with normally functioning PVPs, the mean (SD) peak velocity was 2.33 (0.36) m/s with an average peak pressure gradient of 22.69 (6.7) mm Hg and an average mean pressure gradient of 12.5 (4.1) mm Hg. The mean PVPs velocity time integral (VTI) was 47.49 (12.78) cm with mean right ventricle outflow tract/peak velocity (PV) VTI ratio 0.43 (0.14), mean PVPs effective orifice area was 1.63 (0.36) cm(2). Metallic PVPs had significantly better hemodynamic Doppler study compared with biologic PVPs. In 9 patients with PVP malfunction, average peak PVPs velocity, average peak pressure gradient, mean pressure gradient, PV VTI, PV/left ventricle outflow tract VTI ratio was significantly increased (P < 0.05).
This study contributes to establishing the normal range for Doppler hemodynamics in various PVPs.
关于肺动脉瓣假体(PVP)的多普勒超声心动图数据的报道较少。本研究的目的是提供对PVP的全面多普勒超声心动图评估。
我们研究了40例(平均年龄24.2岁)使用PVP的患者:13例(32.5%)使用机械瓣膜,27例(67.5%)使用生物瓣膜。经过临床评估后,所有患者均接受了完整的二维和多普勒检查。
在30例PVP功能正常的患者中,平均(标准差)峰值速度为2.33(0.36)米/秒,平均峰值压力阶差为22.69(6.7)毫米汞柱,平均平均压力阶差为12.5(4.1)毫米汞柱。PVP的平均速度时间积分(VTI)为47.49(12.78)厘米,右心室流出道/峰值速度(PV)VTI的平均比值为0.43(0.14),PVP的平均有效瓣口面积为1.63(0.36)平方厘米。与生物PVP相比,金属PVP的血流动力学多普勒研究结果明显更好。在9例PVP功能障碍的患者中,PVP的平均峰值速度、平均峰值压力阶差、平均压力阶差、PV VTI、PV/左心室流出道VTI比值均显著增加(P<0.05)。
本研究有助于确定各种PVP多普勒血流动力学的正常范围。