Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55905, USA.
J Am Soc Echocardiogr. 2011 Apr;24(4):414-24. doi: 10.1016/j.echo.2010.12.021. Epub 2011 Jan 17.
Doppler-derived hemodynamic data for normal tricuspid mechanical valve prostheses are limited.
A comprehensive retrospective Doppler echocardiographic assessment of 78 normal St. Jude Medical Standard (St. Jude Medical, Inc., St. Paul, MN), CarboMedics Standard (CarboMedics, Inc., Sorin Group, Burnaby, British Columbia, Canada), and Starr-Edwards (Edwards Lifesciences, LLC, Irvine, CA) mechanical tricuspid valve prostheses was performed early after implantation. We used all the important Doppler-derived hemodynamic variables reported to date, including peak early diastolic velocity (E velocity), mean gradient, pressure half-time, time velocity integral of the tricuspid valve prosthesis (TVI(TVP)), and ratio of the time velocity integral of the tricuspid valve prosthesis to the time velocity integral of the left ventricular outflow tract (TVI(TVP)/TVI(LVOT)).
The mean values obtained for the Doppler parameters did not differ significantly when the measurements from five or nine consecutive cardiac cycles were averaged. Pressure half-time was <130 msec in all 43 patients with St. Jude Medical Standard and CardioMedics Standard prostheses in whom it could be measured. Mean gradient <6 mm Hg, E velocity <1.9 m/s, TVI(TVP) <46 cm, and TVI(TVP)/TVI(LVOT) <2.1 were recorded in 59 (87%) of the 68 patients with either of these prostheses. Hemodynamic variables were considerably less favorable in patients with Starr-Edwards prostheses.
These calculated threshold values (mean + 2 SD) are useful for identifying normal tricuspid mechanical valve function. Prostheses with values for hemodynamic variables that are outside the mean + 2 SD parameters that we have calculated are most likely to be dysfunctional. However, in rare cases, mechanical tricuspid valve prostheses may be dysfunctional even when their hemodynamic parameters are within these specified ranges because of small body surface area or other factors.
多普勒衍生的正常三尖瓣机械瓣膜的血流动力学数据有限。
对 78 例植入早期的正常圣犹达标准(St. Jude Medical Inc.,明尼苏达州圣保罗)、CarboMedics 标准(CarboMedics Inc.,Sorin 集团,不列颠哥伦比亚省本拿比)和 Starr-Edwards(爱德华兹生命科学公司,加利福尼亚州欧文)机械三尖瓣瓣膜进行全面的回顾性多普勒超声心动图评估。我们使用了迄今为止报告的所有重要的多普勒衍生血流动力学变量,包括峰值早期舒张速度(E 速度)、平均梯度、压力半衰期、三尖瓣瓣膜时间速度积分(TVI(TVP))和三尖瓣瓣膜时间速度积分与左心室流出道时间速度积分的比值(TVI(TVP)/TVI(LVOT))。
当将五个或九个连续心动周期的测量值平均时,获得的多普勒参数的平均值没有显著差异。在可以测量的 43 例植入圣犹达标准和 CarboMedics 标准瓣膜的患者中,压力半衰期均<130ms。在植入这些瓣膜的 68 例患者中的 59 例(87%)中,记录到平均梯度<6mmHg、E 速度<1.9m/s、TVI(TVP)<46cm 和 TVI(TVP)/TVI(LVOT)<2.1。Starr-Edwards 瓣膜的患者血流动力学变量明显较差。
这些计算的阈值(均值+2 个标准差)有助于识别正常三尖瓣机械瓣膜功能。血流动力学变量值超出我们计算的均值+2 个标准差参数的瓣膜极有可能功能失调。然而,在极少数情况下,即使机械三尖瓣瓣膜的血流动力学参数在这些特定范围内,由于体表面积较小或其他因素,瓣膜也可能功能失调。