Zhang Qing Hang, Zhou Yuan Li, Petit Dominique, Teo Ee Chon
School of Mechanical and Aerospace Engineering, 50 Nanyang Ave, Nanyang Technological University, Singapore 639798, Singapore.
Med Eng Phys. 2009 Jun;31(5):533-8. doi: 10.1016/j.medengphy.2008.09.011. Epub 2008 Nov 26.
In the current study, finite element analyses were conducted to examine the biomechanical capability of a newly design dynamic stabilization system, FlexPLUS, to restore the load transmission of degenerated intervertebral L4-L5 lumbar motion segment spine under compression. Detailed three-dimensional FE models of L4-L5 motion segment and the FlexPLUS were developed. Compressive loading up to 1000N was applied to the intact L4-L5 model, the L4-L5 models with slight and moderate degenerated disc, and the implanted L4-L5 model. Further more, the load transmission characteristics of Dynesys and a rigid rod was also simulated for comparison. The resultant load-displacement curves and the load transferred through annulus under various conditions were compared. The predicted axial displacement of L4 top surface against applied compressive force of the intact L4-L5 model agreed well with experimental data. The predicted results showed that degenerated disc has significant effect on the lumbar segment load bearing capacity. Not only the stiffness of the segment was greatly increased, the uniform nature of the disc stress distribution was also altered. The FlexPLUS can effectively reduce the disc loading of degenerated model. Although the non-uniform load distribution pattern through annulus was not improved, the overall stress magnitude was greatly reduced to the level of intact model for grade II degeneration.
在当前研究中,进行了有限元分析,以检验一种新设计的动态稳定系统FlexPLUS在压缩状态下恢复退变的L4-L5腰椎运动节段脊柱负荷传递的生物力学能力。建立了L4-L5运动节段和FlexPLUS的详细三维有限元模型。对完整的L4-L5模型、伴有轻度和中度椎间盘退变的L4-L5模型以及植入FlexPLUS的L4-L5模型施加高达1000N的压缩载荷。此外,还模拟了Dynesys和刚性棒的负荷传递特性以作比较。比较了各种条件下所得的载荷-位移曲线以及通过纤维环传递的载荷。完整L4-L5模型的L4上表面相对于施加的压缩力的预测轴向位移与实验数据吻合良好。预测结果表明,退变的椎间盘对腰椎节段的承载能力有显著影响。不仅节段的刚度大大增加,椎间盘应力分布的均匀性也发生了改变。FlexPLUS可有效降低退变模型的椎间盘负荷。虽然通过纤维环的非均匀负荷分布模式没有得到改善,但对于II级退变,整体应力大小大大降低至完整模型的水平。