Misiara Gustavo P, Troncon Luiz E A, Moraes Eder R, Secaf Marie
Division of Gastroenterology and Section of Nuclear Medicine, Department of Medicine, Faculdade de Medicina de Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil.
Ann Nucl Med. 2008 Nov;22(9):761-7. doi: 10.1007/s12149-008-0182-8. Epub 2008 Nov 28.
This work aimed at determining whether data from dynamic antral scintigraphy (DAS) yielded by a simple, manual technique are as accurate as those generated by a conventional automated technique (fast Fourier transform) for assessing gastric contractility.
Seventy-one stretches (4 min) of "activity versus time" curves obtained by DAS from 10 healthy volunteers and 11 functional dyspepsia patients, after ingesting a liquid meal (320 ml, 437 kcal) labeled with technetium-99m (99mTc)-phytate, were independently analyzed by manual and automated techniques.
Data obtained by both techniques for the frequency of antral contractions were similar. Contraction amplitude determined by the manual technique was significantly higher than that estimated by the automated method, in both patients and controls. The contraction frequency 30 min post-meal was significantly lower in patients than in controls, which was correctly shown by both techniques.
A manual technique using ordinary resources of the gamma camera workstation, despite yielding higher figures for the amplitude of gastric contractions, is as accurate as the conventional automated technique of DAS analysis. These findings may favor a more intensive use of DAS coupled to gastric emptying studies, which would provide a more comprehensive assessment of gastric motor function in disease.
本研究旨在确定通过一种简单的手动技术获得的动态胃窦闪烁扫描（DAS）数据，对于评估胃收缩功能而言，是否与传统的自动技术（快速傅里叶变换）所产生的数据一样准确。
10名健康志愿者和11名功能性消化不良患者在摄入用99m锝（99mTc）-植酸盐标记的流质餐（320毫升，437千卡）后，通过DAS获得了71段（4分钟）“活性与时间”曲线，分别用手动和自动技术进行独立分析。
两种技术所获得的胃窦收缩频率数据相似。在患者和对照组中，手动技术测定的收缩幅度均显著高于自动方法估计的收缩幅度。餐后30分钟患者的收缩频率显著低于对照组，两种技术均正确显示了这一点。
使用γ相机工作站的常规资源的手动技术，尽管胃收缩幅度的数据较高，但与DAS分析的传统自动技术一样准确。这些发现可能有利于更广泛地将DAS与胃排空研究相结合，从而对疾病中的胃运动功能进行更全面的评估。
