Bonifaz Alexandro, Tirado-Sánchez Andrés, Ponce Rosa María
Departamento de Micología, Hospital General de México, SSA, México D. F., México.
Gac Med Mex. 2008 Sep-Oct;144(5):427-33.
Majocchi's granuloma or dermatophytic granuloma is a mycosis observed among immunocompetent and immunocompromised patients caused by dermatophytes, particularly Trichophyton rubrum, which may be responsible for 50% of cases. The mechanism by which it occurs is yet unknown although reports suggest it may occur after localized trauma that alters the hair follicle and enables the entrance of the microorganism. Diabetes and the use of topical steroids are among some of the predispEl cuadro 1 no está acotado. Favor de hacerloEl cuadro 1 no está acotado. Favor de hacerloosing factors. Majocchi's granuloma has two clinical presentations, among immunocompetent patients it displays follicular papules and among immunocom-promised patients a subcutaneous nodular type is observed. Diagnosis is confirmed through histopathology, where granulomas and dermatophytes in the form of filaments or spores are observed in the mid and deep dermis. Treatment includes systemic antimycotics. We reviewed the etiopathogenic, clinical, histopathological and therapeutic aspects of Majocchi's granuloma.
Majocchi肉芽肿或皮肤癣菌性肉芽肿是一种在免疫功能正常和免疫功能低下患者中观察到的真菌病,由皮肤癣菌引起,尤其是红色毛癣菌,它可能导致50%的病例。其发生机制尚不清楚,尽管有报告表明它可能在局部创伤改变毛囊并使微生物进入后发生。糖尿病和局部使用类固醇是一些易感因素。Majocchi肉芽肿有两种临床表现,在免疫功能正常的患者中表现为毛囊丘疹,在免疫功能低下的患者中观察到皮下结节型。通过组织病理学确诊,在真皮中层和深层观察到肉芽肿和呈细丝或孢子形式的皮肤癣菌。治疗包括全身抗真菌药。我们回顾了Majocchi肉芽肿的病因、临床、组织病理学和治疗方面。