Department of Dermatology, The Third Affiliated Hospital of Soochow University, Changzhou, 213003, Jiangsu, China.
Ann Clin Microbiol Antimicrob. 2020 Sep 2;19(1):39. doi: 10.1186/s12941-020-00382-y.
Majocchi's granuloma is an uncommon fungal infection of the dermis and subcutaneous tissue. The most frequently identified cause of Majocchi's granuloma is anthropophilic Trichophyton rubrum, and it is most commonly located on the anterior aspect of the lower limbs in women. Here, we report a case of Majocchi's granuloma on the forearm, a site that is rarely involved, in a 62-year-old woman who had been bitten by a dog. Histological examination revealed a dense dermal infiltrate composed of lymphoplasmacytic cells and neutrophils, with hyphae in the dermis. The presence of the fungus, Trichophyton tonsurans, was confirmed by mycological examination and molecular methods. Therefore, histological and mycological examination confirmed the diagnosis of Majocchi's granuloma. The patient was treated with local moxibustion and itraconazole, 200 mg/day, for 60 days, which facilitated a complete resolution of the lesions.
马乔基氏肉芽肿是一种罕见的真皮和皮下组织真菌感染。马乔基氏肉芽肿最常被确认的病因是亲人性亲动物性红色毛癣菌,它最常位于下肢的前侧,多见于女性。在此,我们报告了一例发生在前臂的马乔基氏肉芽肿病例,该部位很少受累,患者为 62 岁女性,曾被狗咬伤。组织学检查显示真皮内有密集的淋巴浆细胞和中性粒细胞浸润,真皮内有菌丝。真菌,须癣毛癣菌,通过真菌学检查和分子方法得到确认。因此,组织学和真菌学检查证实了马乔基氏肉芽肿的诊断。患者接受了局部艾灸和伊曲康唑治疗,每日 200 毫克,共 60 天,病变完全消退。