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免疫功能正常患者面部的Majocchi肉芽肿。

Majocchi's granuloma of the face in an immunocompetent patient.

作者信息

Gill Meenu, Sachdeva Bhavna, Gill Paramjeet S, Arora Brijbala, Deep Antariksh, Karan Jai

机构信息

Department of Pathology, PGIMS, Rohtak, Haryana, India.

出版信息

J Dermatol. 2007 Oct;34(10):702-4. doi: 10.1111/j.1346-8138.2007.00363.x.

DOI:10.1111/j.1346-8138.2007.00363.x
PMID:17908142
Abstract

Majocchi's granuloma is a condition with chronic erythematous and indurated plaques that is a result of the rupture of a dermatophyte-infected infundibulum as a result of trauma. It is frequently seen on the anterior aspect of the legs of women. Herein, we present a case of Majocchi's granuloma of face, a site rarely involved, in an immunocompetent patient. Diagnosis was confirmed by histological and mycological examination. Histological examination revealed hyphae and arthrospores in the hair follicles and in the dermis with a diffuse dermal infiltrate consisting of lymphoplasmacytic cells, and focal collections of epithelioid cells, neutrophils and mild interstitial edema. Mycological examination confirmed the presence of fungus, Trichophyton rubrum, and the diagnosis of Majocchi's granuloma of the face was made. No concrete predisposing factor was found to be associated with the occurrence of the lesions on the face. However, the history of prolonged veiling of the face by a cloth by the patient, perhaps contributing to the occurrence of lesions on face, is a point of dubious significance.

摘要

Majocchi 肉芽肿是一种表现为慢性红斑和硬结性斑块的疾病,是由于创伤导致皮肤癣菌感染的漏斗部破裂所致。它常见于女性腿部前侧。在此,我们报告一例免疫功能正常患者发生在面部(该部位很少受累)的 Majocchi 肉芽肿病例。通过组织学和真菌学检查确诊。组织学检查显示毛囊和真皮内有菌丝和关节孢子,真皮弥漫性浸润,由淋巴细胞和浆细胞组成,并有上皮样细胞、中性粒细胞灶性聚集和轻度间质水肿。真菌学检查证实存在红色毛癣菌,从而做出面部 Majocchi 肉芽肿的诊断。未发现与面部病变发生相关的具体诱发因素。然而,患者长期用布蒙面的病史,可能促成了面部病变的发生,其意义尚不确定。

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引用本文的文献

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Unusual Inflammatory Tinea Infections: Majocchi's Granuloma and Deep/Systemic Dermatophytosis.罕见的炎症性癣感染:Majocchi 肉芽肿和深部/系统性皮肤癣菌病。
J Fungi (Basel). 2021 Oct 31;7(11):929. doi: 10.3390/jof7110929.
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Majocchi's granuloma on the forearm caused by Trichophyton tonsurans in an immunocompetent patient.前臂由须癣毛癣菌引起的 Majocchi 肉芽肿,发生于免疫功能正常的患者。
Ann Clin Microbiol Antimicrob. 2020 Sep 2;19(1):39. doi: 10.1186/s12941-020-00382-y.
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Severe Dermatophytosis and Acquired or Innate Immunodeficiency: A Review.
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J Fungi (Basel). 2015 Dec 31;2(1):4. doi: 10.3390/jof2010004.
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Management of tinea corporis, tinea cruris, and tinea pedis: A comprehensive review.体癣、股癣和足癣的管理:全面综述。
Indian Dermatol Online J. 2016 Mar-Apr;7(2):77-86. doi: 10.4103/2229-5178.178099.
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Successful Treatment of Refractory Majocchi's Granuloma with Voriconazole and Review of Published Literature.伏立康唑成功治疗难治性马约基氏肉芽肿并文献综述
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Case for diagnosis.诊断病例
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