Ogata Kenichi, Morooka Mitsuyuki
Department of Pulmonary Disease, Shindenbaru Holy Mother Hospital.
Nihon Kokyuki Gakkai Zasshi. 2008 Oct;46(10):853-7.
An 82-year-old man with fever and a cough was admitted to hospital. A chest radiograph demonstrated infiltrative shadows in the bilateral middle and lower lung fields and a chest CT scan showed the shadows in the bilateral upper and lower lobes. After admission, infiltrative shadows in the right upper lobe increased and transbronchial lung biopsy (TBLB) specimens disclosed organizing exudates in the alveolar spaces. After steroid treatment, the radiographic infiltrates disappeared but the irregular shadows in the right lower lobe were still present. Lung adenocarcinoma was diagnosed by TBLB specimens of residual shadows. Few cases of cryptogenic organizing pneumonia (COP) with lung cancer have been reported, and further consideration should be given to the relationship between COP and lung cancer. We should consider that diagnostic preparations for chest radiographic imaging can lead to the recognition of several respiratory diseases.
一名82岁发热伴咳嗽的男性患者入院。胸部X线片显示双侧中、下肺野有浸润性阴影,胸部CT扫描显示双侧上、下叶有阴影。入院后,右上叶浸润性阴影增大,经支气管肺活检(TBLB)标本显示肺泡腔内有组织性渗出物。类固醇治疗后,影像学上的浸润影消失,但右下叶的不规则阴影仍存在。通过残留阴影的TBLB标本诊断为肺腺癌。很少有隐源性机化性肺炎(COP)合并肺癌的病例报道,应进一步考虑COP与肺癌之间的关系。我们应该认识到胸部影像学检查的诊断准备可能会发现多种呼吸系统疾病。