Csáky G, Balázs G, Bakó G, Ilyés I, Kálmán K, Szabó J
Department of Surgery, County Hospital, Miskolc, Hungary.
Prog Pediatr Surg. 1991;26:31-40. doi: 10.1007/978-3-642-88324-8_5.
The authors report on the complex follow-up of 60 patients operated on for hyperthyroidism in childhood, on average 13.7 years after surgery. In 16.7% of the patients manifest hypothyroidism, in 45% subclinical hypothyroidism was found; 30% of the patients were euthyroid, and manifest hyperthyroidism recurred in 8.3%. Autonomous adenomas were enucleated in two children and three young adults. Severe disorders in thyroid function developed especially after the surgery of diffuse toxic goiters accompanied by ophthalmopathy. The disorders of humoral and cellular immunity were detected most frequently in recurrent manifest hyperthyroidism. There was no case where ophthalmopathy progressed after the operation. In the offspring of the operated patients the incidence of hyperthyroidism was not increased in childhood. The authors call attention to the importance of postoperative follow-up and hormone treatment.
作者报告了60例童年期接受甲亢手术患者的复杂随访情况，平均随访时间为术后13.7年。16.7%的患者出现甲状腺功能减退，45%的患者发现亚临床甲状腺功能减退；30%的患者甲状腺功能正常，8.3%的患者甲亢复发。两名儿童和三名年轻人的自主性腺瘤被摘除。甲状腺功能严重紊乱尤其在伴有眼病的弥漫性毒性甲状腺肿手术后出现。体液和细胞免疫紊乱在复发的显性甲亢中最常被检测到。术后没有一例眼病进展的情况。手术患者的后代在童年期甲亢发病率并未增加。作者提醒注意术后随访和激素治疗的重要性。
