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用于人类疾病研究的疾病模型多得令人困惑——科学家如何在海量数据中找到方向并获得指导呢?

The baffling multitude of disease models for the study of human disease--how can the scientist navigate the huge amount of data and receive guidance?

作者信息

Chang Michael C, Grieder Franziska B

机构信息

Division of Comparative Medicine, National Center for Research Resources, NIH, 6701 Democracy Blvd, Bethesda, MD 20892, USA.

出版信息

Dis Model Mech. 2008 Sep-Oct;1(2-3):99-102. doi: 10.1242/dmm.001354.

DOI:10.1242/dmm.001354
PMID:19048071
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2562189/
Abstract

Funding from external sources is the lifeline for most biomedical research scientists. In the USA, the National Institutes of Health (NIH), composed of 27 institutes and centers, is the primary federal agency for conducting and supporting medical research. One of these centers, the National Center for Research Resources (NCRR) provides financial support and resources to clinical or translational scientists working to understand human disease. Through the Division of Comparative Medicine, the NCRR funds projects focused on the development and use of model organisms to understand, diagnose, prevent and treat disease. Here, officials within the NCRR's Division of Comparative Medicine discuss some of the funding opportunities and resources available to researchers who use model organisms, and their perspectives on the future of model organism research.

摘要

外部资金是大多数生物医学研究科学家的生命线。在美国,由27个研究所和中心组成的国立卫生研究院(NIH)是开展和支持医学研究的主要联邦机构。其中一个中心,国家研究资源中心(NCRR)为致力于了解人类疾病的临床或转化科学家提供资金支持和资源。通过比较医学部,NCRR为专注于开发和使用模式生物以了解、诊断、预防和治疗疾病的项目提供资金。在此,NCRR比较医学部的官员讨论了一些可供使用模式生物的研究人员获得的资金机会和资源,以及他们对模式生物研究未来的看法。

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本文引用的文献

1
Teaching "one medicine, one health".传授“同一医学,同一健康”理念。
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Medicine. Initiative aims to merge animal and human health science to benefit both.医学。该倡议旨在融合动物与人类健康科学,使两者均受益。
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