Roochvarg L B, Lovchik J C
Department of Pediatrics, University of Maryland Medical School, Baltimore 21201.
J Adolesc Health. 1991 May;12(3):269-72. doi: 10.1016/0197-0070(91)90022-e.
The cost-effectiveness of screening for pharyngeal gonorrhea (PG) in an adolescent clinic population was examined in the context of dramatically decreasing prevalence. Chart review revealed that the apparent PG prevalence had decreased from 15/555 (2.7%) 8 years ago to 0/319 (0.0%) recently in the clinic population studied. The earlier high prevalence of PG probably represented poor laboratory test specificity. Cost analysis showed that only at very high prevalence of PG (greater than 8%) would pharyngeal screening be cost-effective unless PG can be shown to be an important source of genital infection. We concluded that continued pharyngeal screening is not justified in our clinic because prevalence is so low.
在咽淋病(PG)患病率急剧下降的背景下,对青少年诊所人群中PG筛查的成本效益进行了研究。病历审查显示,在所研究的诊所人群中,PG的明显患病率已从8年前的15/555(2.7%)降至最近的0/319(0.0%)。早期PG的高患病率可能代表实验室检测特异性较差。成本分析表明,除非能证明PG是生殖器感染的重要来源,否则只有在PG患病率非常高(大于8%)时,咽部筛查才具有成本效益。我们得出结论,由于患病率如此之低,在我们的诊所继续进行咽部筛查是不合理的。