Giladi M, Aderka D, Zeligman-Melatzki L, Finkelstein A, Ayalon D, Levo Y
Dept. of Medicine T, Ichilov Hospital, Tel Aviv, Israel.
Int J Cardiol. 1991 Mar;30(3):309-13. doi: 10.1016/0167-5273(91)90008-d.
In this study we evaluated the possible relationship between idiopathic atrial fibrillation and occult thyrotoxicosis, diagnosed by lack of response of thyroid stimulating hormone to administration of thyrotropin releasing hormone. Three groups were compared: 25 patients with idiopathic atrial fibrillation; 52 with cardiovascular atrial fibrillation; and 27 with sinus rhythm. Patients were excluded with any clinical evidence of thyrotoxicosis or with elevated serum FT4 level, as well as those with diseases or on medications known to be associated with a diminished response to administration of the releasing hormone. A flat test (lack of response) was found in only 4% of the patients. There was no significant difference among the 3 groups. Based on these data we believe that there is no relationship between idiopathic atrial fibrillation or any other type of atrial fibrillation and occult thyrotoxicosis.
在本研究中，我们评估了特发性心房颤动与隐匿性甲状腺毒症之间的可能关系，隐匿性甲状腺毒症通过促甲状腺激素对促甲状腺激素释放激素给药无反应来诊断。比较了三组：25例特发性心房颤动患者；52例心血管性心房颤动患者；以及27例窦性心律患者。排除有任何甲状腺毒症临床证据或血清FT4水平升高的患者，以及患有已知与释放激素给药反应减弱相关疾病或正在服用相关药物的患者。仅4%的患者出现无反应试验（无反应）。三组之间无显著差异。基于这些数据，我们认为特发性心房颤动或任何其他类型的心房颤动与隐匿性甲状腺毒症之间没有关系。
