Ciaccheri M, Cecchi F, Arcangeli C, Dolara A, Zuppiroli A, Pieroni C
Clin Cardiol. 1984 Jul;7(7):413-6. doi: 10.1002/clc.4960070706.
Thyroid function tests, including thyrotropin releasing hormone administration (TRH), were performed in 40 consecutive patients with isolated atrial fibrillation (IAF) (i.e., without any other evidence of cardiac disease). The arrhythmia was chronic in 5 and paroxysmal in 35 patients. Thyrotoxicosis could not be diagnosed either clinically or by abnormal serum levels of T4, T3, T3 BC, and thyroid stimulating hormone (TSH). Thyroid stimulating hormone response to TRH, which was normal in 35 patients, was absent in 5 (12.5%) who were considered to have occult thyrotoxicosis. One had chronic and the other 4 had paroxysmal IAF. The arrhythmia did not recur after antithyroid treatment in these four patients who were in sinus rhythm after a mean follow-up period of 21 months. Full exploration of the thyroid function therefore seems useful not only in patients with chronic IAF, but also in those affected by the paroxysmal form.
对40例连续性孤立性心房颤动（IAF）患者（即无任何其他心脏病证据）进行了甲状腺功能检查，包括促甲状腺激素释放激素注射试验（TRH）。5例患者为慢性心律失常，35例为阵发性心律失常。无论是临床诊断还是通过血清T4、T3、T3 BC及促甲状腺激素（TSH）水平异常均无法诊断甲状腺毒症。35例患者对TRH的促甲状腺激素反应正常，5例（12.5%）无反应，这5例被认为患有隐匿性甲状腺毒症。其中1例为慢性IAF，另外4例为阵发性IAF。这4例患者在平均21个月的随访期后处于窦性心律，接受抗甲状腺治疗后心律失常未复发。因此，全面评估甲状腺功能不仅对慢性IAF患者有用，对阵发性IAF患者也似乎有用。
