Nemes Attila, Leung Ka Yan Esther, van Burken Gerard, van Stralen Marijn, Bosch Johan G, Soliman Osama I I, Krenning Boudewijn J, Vletter Wim B, ten Cate Folkert J, Geleijnse Marcel L
Department of Cardiology, Thoraxcentre, Erasmus MC, Rotterdam, The Netherlands.
Echocardiography. 2009 Feb;26(2):189-95. doi: 10.1111/j.1540-8175.2008.00796.x. Epub 2008 Nov 7.
Dobutamine stress echocardiography (DSE) suffers from high interobserver and inter-institution variability in the diagnosis of myocardial ischemia. Therefore, we developed a three-dimensional (3D) analysis tool that makes it possible to anatomically align 3D rest and stress data systematically, to generate optimal, nonforeshortened standard anatomical cross sections and to analyse the images synchronized and side-by-side.
To investigate whether this 3D analysis tool could improve interobserver agreement on myocardial ischemia during 3D DSE.
The study comprised 34 consecutive patients with stable chest pain who underwent both noncontrast and contrast 3D DSE. Two observers scored segmental wall motion using a conventional analysis and the novel analysis with the new 3D tool.
The two observers agreed on the presence or absence of myocardial ischemia in 81 of 102 coronary territories (agreement 79%, kappa (kappa) 0.28) during noncontrast 3D imaging and 92 of 102 coronary territories (agreement 90%, kappa 0.65) during contrast-enhanced 3D imaging. With the new 3D analysis software these numbers improved to 98 of 102 coronary territories (agreement 96%, kappa 0.69) during noncontrast 3D imaging and 98 of 102 coronary territories (agreement 96%, kappa 0.82) during contrast-enhanced 3D imaging.
The use of a 3D DSE analysis tool improves interobserver agreement for myocardial ischemia both for noncontrast and contrast images.
多巴酚丁胺负荷超声心动图(DSE)在心肌缺血诊断中存在较高的观察者间和机构间变异性。因此,我们开发了一种三维(3D)分析工具,该工具能够系统地对三维静息和负荷数据进行解剖学对齐,生成最佳的、无缩短的标准解剖横截面,并对同步并排的图像进行分析。
探讨这种三维分析工具能否提高三维DSE期间观察者间对心肌缺血的一致性。
该研究纳入了34例连续的稳定型胸痛患者,他们均接受了非对比剂和对比剂三维DSE检查。两名观察者分别使用传统分析方法和新的三维工具进行的新颖分析方法对节段性室壁运动进行评分。
在非对比剂三维成像期间,两名观察者在102个冠状动脉节段中的81个节段上对心肌缺血的存在与否达成一致(一致性为79%,kappa值为0.28);在对比剂增强三维成像期间,在102个冠状动脉节段中的92个节段上达成一致(一致性为90%,kappa值为0.65)。使用新的三维分析软件后,在非对比剂三维成像期间,这些数字提高到102个冠状动脉节段中的98个节段(一致性为96%,kappa值为0.69);在对比剂增强三维成像期间,为102个冠状动脉节段中的98个节段(一致性为96%,kappa值为0.82)。
使用三维DSE分析工具可提高非对比剂和对比剂图像观察者间对心肌缺血的一致性。