一种治疗铅中毒的口服疗法。
An oral treatment for lead toxicity.
作者信息
Thomas P S, Ashton C
机构信息
Northwick Park Hospital, Harrow, Middlesex, UK.
出版信息
Postgrad Med J. 1991 Jan;67(783):63-5. doi: 10.1136/pgmj.67.783.63.
Abstract
Chronic lead poisoning has traditionally been treated by parenteral agents. We present a case where a comparison of ethylene diaminetetra-acetic acid was made with 2,3-dimethyl succinic acid (DMSA) which has the advantage of oral administration associated with little toxicity and appeared to be at least as efficacious.
摘要
传统上，慢性铅中毒采用肠胃外给药进行治疗。我们报告了一例病例，该病例对乙二胺四乙酸与2,3-二甲基琥珀酸（DMSA）进行了比较，DMSA具有口服优势，毒性小，且疗效似乎至少相当。
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引用本文的文献
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An oral treatment for lead toxicity.一种治疗铅中毒的口服疗法。
Postgrad Med J. 1991 Oct;67(792):953. doi: 10.1136/pgmj.67.792.953.
本文引用的文献
1
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Annu Rev Pharmacol Toxicol. 1983;23:193-215. doi: 10.1146/annurev.pa.23.040183.001205.
2
[Lead poisoning treated with 2,3-dimercaptosuccinic acid].
Presse Med. 1984 Oct 13;13(36):2209.
3
Chelating therapy with Na-DMS in occupational lead and mercury intoxications.
Chin Med J. 1965 Jul;84(7):437-9.
4
Comparative mobilization of lead by chelating agents.螯合剂对铅的相对动员作用。
Toxicology. 1988 Dec 30;53(2-3):277-88. doi: 10.1016/0300-483x(88)90220-x.
5
Mobilization and redistribution of lead over the course of calcium disodium ethylenediamine tetraacetate chelation therapy.在乙二胺四乙酸二钠钙螯合治疗过程中铅的动员与再分布
J Pharmacol Exp Ther. 1987 Dec;243(3):804-13.
6
Meso-2,3-dimercaptosuccinic acid in the diagnosis and treatment of lead poisoning.
J Toxicol Clin Toxicol. 1987;25(1-2):39-51. doi: 10.3109/15563658708992612.
7
2,3-Dimercaptosuccinic acid as an antidote for lead intoxication.
Clin Pharmacol Ther. 1985 Apr;37(4):431-8. doi: 10.1038/clpt.1985.67.
8
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Med Toxicol Adverse Drug Exp. 1988 Nov-Dec;3(6):499-504. doi: 10.1007/BF03259898.
9
Dose-response study of oral 2,3-dimercaptosuccinic acid in children with elevated blood lead concentrations.
J Pediatr. 1988 Oct;113(4):751-7. doi: 10.1016/s0022-3476(88)80396-2.
10
Mobilization of lead over the course of DMSA chelation therapy and long-term efficacy.二巯基丁二酸螯合疗法过程中铅的动员及长期疗效。
J Pharmacol Exp Ther. 1988 Jul;246(1):84-91.
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