Sicras-Mainar Antoni, Velasco-Velasco Soledad, González-Rojas Guix Nuria, Clemente-Igeño Chencho, Rodríguez-Cid José Luis
Dirección de Planificación y Desarrollo Organizativo. Badalona Serveis Assistencials S.A. Badalona. Barcelona. España.
Aten Primaria. 2008 Sep;40(9):447-54. doi: 10.1157/13126421.
To determine the comorbidity, the therapeutic objectives, and economic impact in subjects with cardiovascular risk in primary care (PC).
Multicentre, cross-sectional study.
Five urban PC centres, Spain.
Patients over 55 years seen during the year 2006. Compared according to the presence/absence of a cardiovascular event (CVE).
Demographics, cardiovascular/general comorbidity (adjusted clinical groups), Charlson index, clinical parameters, multiple drugs and semi-fixed direct costs (operational) and variables (tests, referrals, drugs). A logistical regression and ANCOVA analysis was performed to correct the models. SPSSWIN Program (P< .05).
Of 24 410 patients, 15.4% (CI, 14.9-15.9) had a CVE. The subjects with a CVE showed a higher mortality (4.0% vs 1.8%) and general morbidity (8.1 vs 6.4 episodes) (P< .001). The CVE had an independent association in males (OR=2.7), Charlson index (OR=2.1), dyslipaemia (OR=1.5), depression (OR=1.4), age (OR=1.3), arterial hypertension (OR=1.2) and diabetes (OR=1.1) (P< .005). In primary prevention worse average cholesterols were obtained (211.6 vs 192.4 mg/dL), while in secondary prevention blood glucose was worse (111.3 vs 104.2 mg/dL; P< .001). The average corrected direct costs were euro1543.55 versus euro1027.65, respectively (P< .001). These differences were maintained in all the cost components.
The presence of a CVE is associated with higher comorbidity, causing an increase in costs. The achievement of therapeutic control objectives could be improved, in primary prevention as well as in secondary. Intervention strategies should be increased to modify life styles in these patients.
确定基层医疗中具有心血管风险的患者的合并症、治疗目标及经济影响。
多中心横断面研究。
西班牙五个城市的基层医疗中心。
2006年期间就诊的55岁以上患者。根据是否发生心血管事件(CVE)进行比较。
人口统计学、心血管/一般合并症(调整后的临床分组)、查尔森指数、临床参数、多种药物及半固定直接成本(运营)和变量(检查、转诊、药物)。进行逻辑回归和协方差分析以校正模型。采用SPSSWIN程序(P<0.05)。
在24410例患者中,15.4%(可信区间,14.9 - 15.9)发生了CVE。发生CVE的患者死亡率更高(4.0%对1.8%),一般发病率更高(8.1次对6.4次发作)(P<0.001)。CVE在男性(比值比=2.7)、查尔森指数(比值比=2.1)、血脂异常(比值比=1.5)、抑郁症(比值比=1.4)、年龄(比值比=1.3)、动脉高血压(比值比=1.2)和糖尿病(比值比=1.1)方面存在独立关联(P<0.005)。在一级预防中,平均胆固醇水平更差(211.6对192.4mg/dL),而在二级预防中,血糖水平更差(111.3对104.2mg/dL;P<0.001)。平均校正后的直接成本分别为1543.55欧元和1027.65欧元(P<0.001)。这些差异在所有成本组成部分中均持续存在。
CVE的存在与更高的合并症相关,导致成本增加。在一级预防和二级预防中,治疗控制目标的实现情况均可得到改善。应增加干预策略以改变这些患者的生活方式。