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2
[Comparison of the SCORE function chart and the Framingham-REGICOR equation to estimate the cardiovascular risk in an urban population after 10 years of follow-up].[比较SCORE功能图表与弗雷明汉-REGICOR方程以评估城市人群随访10年后的心血管风险]
Med Clin (Barc). 2006 Sep 16;127(10):368-73. doi: 10.1157/13092437.
3
Increasing trends of acute myocardial infarction in Spain: the MONICA-Catalonia Study.西班牙急性心肌梗死发病率上升趋势:莫妮卡-加泰罗尼亚研究
Eur Heart J. 2005 Mar;26(5):505-15. doi: 10.1093/eurheartj/ehi068. Epub 2004 Dec 15.
4
[Spanish adaptation of the European Guide to Cardiovascular Prevention (I)].《欧洲心血管疾病预防指南》(I)的西班牙语改编版
Aten Primaria. 2004 Nov 15;34(8):427-32. doi: 10.1016/s0212-6567(04)78927-1.
5
Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicentre randomised placebo-controlled trial.阿托伐他汀在2型糖尿病中对心血管疾病的一级预防:合作阿托伐他汀糖尿病研究(CARDS):多中心随机安慰剂对照试验
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6
[Risk factors and 28 year morbidity and mortality of coronary heart disease in a cohort with a low incidence of the disease: the Manresa Study].[疾病低发队列中冠心病的危险因素及28年发病率和死亡率:曼雷萨研究]
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[Patients over-using a primary care centre: their social, demographic and clinical characteristics, and their use of health service facilities].[过度使用初级保健中心的患者:他们的社会、人口统计学和临床特征,以及他们对卫生服务设施的使用情况]
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8
[Evaluation of cardiovascular risk. What table to use?].[心血管风险评估。使用哪种表格?]
Aten Primaria. 2003 Dec;32(10):586-9. doi: 10.1016/s0212-6567(03)79337-8.
9
European guidelines on cardiovascular disease prevention in clinical practice. Third Joint Task Force of European and Other Societies on Cardiovascular Disease Prevention in Clinical Practice.欧洲临床实践中心血管疾病预防指南。欧洲及其他学会心血管疾病预防临床实践联合工作组第三次报告
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An adaptation of the Framingham coronary heart disease risk function to European Mediterranean areas.弗明汉姆冠心病风险函数在欧洲地中海地区的适应性调整。
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[基层医疗环境中心血管疾病风险患者的发病率、代谢控制及资源利用情况的影响]

[Influence of morbidity, metabolic control, and use of resources in subjects with cardiovascular risk in the primary care setting].

作者信息

Sicras-Mainar Antoni, Velasco-Velasco Soledad, González-Rojas Guix Nuria, Clemente-Igeño Chencho, Rodríguez-Cid José Luis

机构信息

Dirección de Planificación y Desarrollo Organizativo. Badalona Serveis Assistencials S.A. Badalona. Barcelona. España.

出版信息

Aten Primaria. 2008 Sep;40(9):447-54. doi: 10.1157/13126421.

DOI:10.1157/13126421
PMID:19054440
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7659846/
Abstract

OBJECTIVE

To determine the comorbidity, the therapeutic objectives, and economic impact in subjects with cardiovascular risk in primary care (PC).

DESIGN

Multicentre, cross-sectional study.

SETTING

Five urban PC centres, Spain.

PARTICIPANTS

Patients over 55 years seen during the year 2006. Compared according to the presence/absence of a cardiovascular event (CVE).

MEASUREMENTS

Demographics, cardiovascular/general comorbidity (adjusted clinical groups), Charlson index, clinical parameters, multiple drugs and semi-fixed direct costs (operational) and variables (tests, referrals, drugs). A logistical regression and ANCOVA analysis was performed to correct the models. SPSSWIN Program (P< .05).

RESULTS

Of 24 410 patients, 15.4% (CI, 14.9-15.9) had a CVE. The subjects with a CVE showed a higher mortality (4.0% vs 1.8%) and general morbidity (8.1 vs 6.4 episodes) (P< .001). The CVE had an independent association in males (OR=2.7), Charlson index (OR=2.1), dyslipaemia (OR=1.5), depression (OR=1.4), age (OR=1.3), arterial hypertension (OR=1.2) and diabetes (OR=1.1) (P< .005). In primary prevention worse average cholesterols were obtained (211.6 vs 192.4 mg/dL), while in secondary prevention blood glucose was worse (111.3 vs 104.2 mg/dL; P< .001). The average corrected direct costs were euro1543.55 versus euro1027.65, respectively (P< .001). These differences were maintained in all the cost components.

CONCLUSIONS

The presence of a CVE is associated with higher comorbidity, causing an increase in costs. The achievement of therapeutic control objectives could be improved, in primary prevention as well as in secondary. Intervention strategies should be increased to modify life styles in these patients.

摘要

目的

确定基层医疗中具有心血管风险的患者的合并症、治疗目标及经济影响。

设计

多中心横断面研究。

地点

西班牙五个城市的基层医疗中心。

参与者

2006年期间就诊的55岁以上患者。根据是否发生心血管事件(CVE)进行比较。

测量指标

人口统计学、心血管/一般合并症(调整后的临床分组)、查尔森指数、临床参数、多种药物及半固定直接成本(运营)和变量(检查、转诊、药物)。进行逻辑回归和协方差分析以校正模型。采用SPSSWIN程序(P<0.05)。

结果

在24410例患者中,15.4%(可信区间,14.9 - 15.9)发生了CVE。发生CVE的患者死亡率更高(4.0%对1.8%),一般发病率更高(8.1次对6.4次发作)(P<0.001)。CVE在男性(比值比=2.7)、查尔森指数(比值比=2.1)、血脂异常(比值比=1.5)、抑郁症(比值比=1.4)、年龄(比值比=1.3)、动脉高血压(比值比=1.2)和糖尿病(比值比=1.1)方面存在独立关联(P<0.005)。在一级预防中,平均胆固醇水平更差(211.6对192.4mg/dL),而在二级预防中,血糖水平更差(111.3对104.2mg/dL;P<0.001)。平均校正后的直接成本分别为1543.55欧元和1027.65欧元(P<0.001)。这些差异在所有成本组成部分中均持续存在。

结论

CVE的存在与更高的合并症相关,导致成本增加。在一级预防和二级预防中,治疗控制目标的实现情况均可得到改善。应增加干预策略以改变这些患者的生活方式。