Murphy G P, Mirand E A, Staubitz W J
Oncology. 1976;33(4):154-6. doi: 10.1159/000225132.
Ectopic tumor associated erythropoietin release was measured preoperatively and postoperatively in 36 Wilms' tumor patients followed for an average of three years. Erythropoietin assay results in plasma and urine were related independently to tumor stage as well as to the general clinical judgment following appropriate and exhaustive tests as to whether the disease was active or inactive at the time of the assay. Consistent erythropoietin plasma elevations were correlated with the presence of active disease in all stages of Wilms' tumor. Less consistent elevations were noted in urine specimens concomitantly obtained and assayed. This hormonal assay continues to be of consistent and long-term benefit in predicting or correlating disease recurrence or persistence in Wilms' tumor.
对36例威尔姆斯瘤患者在术前和术后测量了异位肿瘤相关促红细胞生成素的释放情况，这些患者平均随访了三年。血浆和尿液中促红细胞生成素的检测结果分别与肿瘤分期以及在进行关于检测时疾病是处于活动期还是非活动期的适当且详尽的检查后的总体临床判断相关。在威尔姆斯瘤的所有阶段，促红细胞生成素血浆持续升高与疾病活动状态相关。在同时采集和检测的尿液样本中，促红细胞生成素升高的情况不太一致。这种激素检测在预测或关联威尔姆斯瘤疾病复发或持续存在方面继续具有持续且长期的益处。
