Kayser Sarah, Bewernick Bettina, Axmacher Nikolai, Schlaepfer Thomas E
Department of Psychiatry and Psychotherapy, University Hospital, Bonn, Germany.
J ECT. 2009 Jun;25(2):137-40. doi: 10.1097/YCT.0b013e31817dc45a.
Electroconvulsive therapy (ECT) is a highly efficacious treatment for severe depression. However, a disadvantage of ECT is the risk of cognitive side effects. Magnetic seizure therapy (MST) is a novel treatment modality, by which therapeutic seizures are induced using rapidly alternating strong magnetic fields. In this case study, we report on successful MST treatment of an episode of otherwise treatment-resistant depression in a patient with bipolar I disorder. Compared with published ECT results, MST seizures in this case report were of shorter duration, lower ictal electroencephalogram amplitude, and less pronounced postictal suppression. Furthermore, the patient did not experience subjective side effects and particularly recovered time to full orientation more quickly with MST than what has been previously described for ECT. Taken together, these results suggest that MST, compared with ECT, might have antidepressant effects and may have fewer clinical side effects.
电休克疗法（ECT）是治疗重度抑郁症的一种高效疗法。然而，ECT的一个缺点是存在认知副作用的风险。磁惊厥疗法（MST）是一种新型治疗方式，通过快速交替的强磁场诱发治疗性惊厥。在本病例研究中，我们报告了对一名双相I型障碍患者的一次难治性抑郁症发作成功进行MST治疗的情况。与已发表的ECT结果相比，本病例报告中的MST惊厥持续时间更短、发作期脑电图振幅更低且发作后抑制不那么明显。此外，该患者未经历主观副作用，尤其是与先前描述的ECT相比，MST治疗后恢复完全定向的时间更快。综上所述，这些结果表明，与ECT相比，MST可能具有抗抑郁作用且临床副作用可能更少。
