Gomarus H Karin, Wijers Albertus A, Minderaa Ruud B, Althaus Monika
Department of Child- and Adolescent Psychiatry, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.
Clin Neurophysiol. 2009 Jan;120(1):73-9. doi: 10.1016/j.clinph.2008.10.017. Epub 2008 Dec 5.
We examined whether the method of event-related (de-)synchronization (ERD/ERS) revealed differential effects of selective attention and working memory load in children (8-11 years) with pervasive developmental disorder - not otherwise specified (PDD-NOS) or attention-deficit/hyperactivity disorder (ADHD).
Fifteen healthy controls and three equally large groups of children with symptoms of PDD-NOS, ADHD or both (PDD/HD) performed a visual selective memory search task. The EEG was recorded from which occipital alpha and frontal theta were derived.
The effects of the overall task manipulations of task load, relevance and target/nontarget were clearly present in the overall analyses of alpha and theta ERD/ERS. However, no significant differences with respect to these manipulations existed between any of the subject groups.
The results supply no evidence for a distinction in information processing abilities of selective attention and working memory as reflected by alpha and theta ERD/ERS between children diagnosed with either ADHD, PDD-NOS or healthy controls.
Alpha and theta ERD/ERS are sensitive to manipulations of task load, relevance and target/nontarget, but supply no additional information on possible group differences in comparison to the more frequently used method of event-related potentials.
我们研究了事件相关（去）同步化（ERD/ERS）方法是否揭示了广泛性发育障碍未特定化（PDD-NOS）或注意力缺陷多动障碍（ADHD）的儿童（8至11岁）在选择性注意和工作记忆负荷方面的差异效应。
15名健康对照儿童以及三组同样数量、有PDD-NOS症状、ADHD症状或兼具两种症状（PDD/HD）的儿童执行了一项视觉选择性记忆搜索任务。记录脑电图，从中得出枕叶α波和额叶θ波。
在对α波和θ波ERD/ERS的总体分析中，任务负荷、相关性以及目标/非目标等总体任务操作的效应清晰可见。然而，各受试组在这些操作方面不存在显著差异。
结果未提供证据表明，被诊断为ADHD、PDD-NOS或健康对照的儿童之间，α波和θ波ERD/ERS所反映的选择性注意和工作记忆的信息处理能力存在差异。
α波和θ波ERD/ERS对任务负荷、相关性以及目标/非目标的操作敏感，但与更常用的事件相关电位方法相比，未提供关于可能的组间差异的额外信息。
