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亚热带气候为主地区重伤创伤患者的体温过低及相关后果

Hypothermia and associated outcomes in seriously injured trauma patients in a predominantly sub-tropical climate.

作者信息

Aitken L M, Hendrikz J K, Dulhunty J M, Rudd M J

机构信息

Griffith University, Nathan, QLD 4111, Australia.

出版信息

Resuscitation. 2009 Feb;80(2):217-23. doi: 10.1016/j.resuscitation.2008.10.021. Epub 2008 Dec 6.

Abstract

AIM

This study aimed to determine factors linked to hypothermia (<35 degrees C) in Queensland trauma patients. The relationship of hypothermia with mortality, admission to intensive care and hospital length of stay was also explored.

METHODS

A retrospective analysis of data from the Queensland Trauma Registry was undertaken, and included all patients admitted to hospital for > or =24h during 2003 and 2004 with an injury severity score (ISS)>15. Demographic, injury, environmental, care and clinical status factors were considered.

RESULTS

A total of 2182 patients were included; 124 (5.7%) had hypothermia on admission to the definitive care hospital, while a further 156 (7.1%) developed hypothermia during hospitalisation. Factors associated with hypothermia on admission included winter, direct admission to a definitive care hospital, an ISS> or =40, a Glasgow Coma Scale of 3 or ventilated and sedated, and hypotension on admission. Hypothermia on admission to the definitive care hospital was an independent predictor of mortality (odds ratio [OR]=4.05; 95% confidence interval [CI] 2.26-7.24) and hospital length of stay (incidence rate ratio [IRR]=1.22; 95% CI 1.03-1.43). Hypothermia during definitive care hospitalisation was independently associated with mortality (OR=2.52; 95% CI 1.52-4.17), intensive care admission (OR=1.73; 95% CI 1.20-2.93) and hospital length of stay (IRR=1.18; 95% CI 1.02-1.36).

CONCLUSIONS

Trauma patients in a predominantly sub-tropical climate are at risk of accidental and endogenous hypothermia, with associated higher mortality and care requirements. Prevention of hypothermia is important for all severely injured patients.

摘要

目的

本研究旨在确定与昆士兰创伤患者体温过低(<35摄氏度)相关的因素。同时探讨体温过低与死亡率、入住重症监护病房及住院时间的关系。

方法

对昆士兰创伤登记处的数据进行回顾性分析,纳入2003年和2004年期间因伤入住医院超过或等于24小时且损伤严重度评分(ISS)>15的所有患者。考虑了人口统计学、损伤、环境、护理及临床状况等因素。

结果

共纳入2182例患者;124例(5.7%)在入住确定性治疗医院时体温过低,另有156例(7.1%)在住院期间出现体温过低。入院时体温过低的相关因素包括冬季、直接入住确定性治疗医院、ISS>或=40、格拉斯哥昏迷量表评分为3或接受通气和镇静治疗以及入院时低血压。入住确定性治疗医院时体温过低是死亡率(比值比[OR]=4.05;95%置信区间[CI]2.26 - 7.24)和住院时间(发病率比[IRR]=1.22;95%CI 1.03 - 1.43)的独立预测因素。确定性治疗住院期间体温过低与死亡率(OR=2.52;95%CI 1.52 - 4.17)、入住重症监护病房(OR=1.73;95%CI 1.20 - 2.93)及住院时间(IRR=1.18;95%CI 1.02 - 1.36)独立相关。

结论

在以亚热带气候为主的地区,创伤患者存在意外和内源性体温过低的风险,且伴有较高的死亡率和护理需求。预防体温过低对所有重伤患者都很重要。

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