Zampino Maria Giulia, Labianca Roberto, Beretta Giordano D, Magni Elena, Gatta Gemma, Leonardi Maria Cristina, Chiappa Antonio, Biffi Roberto, de Braud Filippo, Wils Jacques
Medical Care Unit, European Institute of Oncology, Milan, Italy.
Crit Rev Oncol Hematol. 2009 May;70(2):160-82. doi: 10.1016/j.critrevonc.2008.10.010. Epub 2008 Dec 6.
Rectal cancer is an important tumour from an epidemiological point of view and represents the benchmark for an optimal use of integrated treatments (surgery, radiotherapy and chemotherapy) in the oncological practice. The conventional use of total mesorectal excision and the integration with radiochemotherapy, better if preoperatively, are now able to increase survival, to decrease the occurrence of pelvic recurrence and to ameliorate the quality of life of patients. Updated recommendations for the management of these patients are here reported.
从流行病学角度来看，直肠癌是一种重要的肿瘤，也是肿瘤学实践中优化使用综合治疗（手术、放疗和化疗）的基准。全直肠系膜切除术的传统应用以及与放化疗的结合（术前进行效果更佳），如今能够提高生存率、降低盆腔复发率并改善患者生活质量。本文报告了这些患者管理的最新建议。
