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重症肌无力危象

Myasthenic crisis.

作者信息

Chaudhuri A, Behan P O

机构信息

Essex Centre for Neurological Sciences, University of Glasgow, Scotland, UK.

出版信息

QJM. 2009 Feb;102(2):97-107. doi: 10.1093/qjmed/hcn152. Epub 2008 Dec 5.

Abstract

Myasthenic crisis is a life-threatening medical emergency requiring early diagnosis and respiratory assistance. It can affect between one-fifth and one-third of all patients with generalized autoimmune myasthenia gravis. Myasthenic crisis is to be distinguished from other causes of acute neuromuscular paralysis which in most cases, can be achieved clinically. High dose corticosteroids in combination with plasma exchange or immunoglobulin are the cornerstone of treatment for this fully reversible cause of neuromuscular paralysis.

摘要

重症肌无力危象是一种危及生命的医疗急症,需要早期诊断和呼吸支持。它可影响五分之一至三分之一的全身性自身免疫性重症肌无力患者。重症肌无力危象需与急性神经肌肉麻痹的其他病因相鉴别,在大多数情况下,这可通过临床诊断来实现。大剂量皮质类固醇联合血浆置换或免疫球蛋白是这种完全可逆性神经肌肉麻痹病因治疗的基石。

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