Hwang In Hye, Lee Kyung Nam, Kim Il Young, Lee Dong Won, Lee Soo Bong, Kim Dae Seong, Song Sang Heon, Seong Eun Young, Kwak Ihm Soo
From the Department of 1Internal Medicine,Pusan National University School of Medicine,Yangsan and the Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, South Korea.
Exp Clin Transplant. 2014 Dec;12(6):555-8. doi: 10.6002/ect.2013.0203. Epub 2014 Feb 25.
Myasthenia gravis is an autoimmune disease characterized by muscle weakness. Myasthenic crisis is a life-threatening complication of myasthenia gravis precipitated by several factors. We experienced a myasthenic crisis after a deceased-donor kidney transplant in a 35-year-old woman who already had been diagnosed with myasthenia gravis. She received mechanical ventilatory support and intravenous immunoglobulin for treatment of the myasthenic crisis. During the early posttransplant period, she recovered with immediate graft function, and her graft functioning did not deteriorate during the myasthenic crisis. We suggest that physicians be aware of worsening of myasthenia gravis when patients with myasthenia gravis undergo a kidney transplant.
重症肌无力是一种以肌肉无力为特征的自身免疫性疾病。重症肌无力危象是由多种因素引发的重症肌无力的一种危及生命的并发症。我们在一位已被诊断患有重症肌无力的35岁女性接受尸体供肾移植后经历了一次重症肌无力危象。她接受了机械通气支持和静脉注射免疫球蛋白来治疗重症肌无力危象。在移植后的早期，她的移植肾立即恢复功能，并且在重症肌无力危象期间其移植肾功能并未恶化。我们建议，当重症肌无力患者接受肾移植时，医生应意识到重症肌无力可能会加重。
