Kotani J, Sugioka S, Sakuma Y, Umemura A, Momota Y, Ueda Y
Department of Anesthesiology, Osaka Dental University.
Kokyu To Junkan. 1991 May;39(5):471-4.
When cerebral circulatory index (CCI) expressed as inverse of arterial-jugular venous oxygen content difference is measured, venous sampling at the internal jugular bulb needs to be done in order to avoid mixture with extra-cerebral perfusion blood. To estimate the validity of this point, difference of values calculated with blood obtained simultaneously at the jugular superior bulb, the inferior region and the cerebral sinus were examined in monkeys. As a result, no significant differences were found to result from location of the sampling, and significant correlation between PaCO2 and CCI was recognized. These findings supported the idea that CCI reflects the cerebral blood flow due to PaCO2 changes.
当测量以动脉-颈静脉血氧含量差的倒数表示的脑循环指数（CCI）时，需要在颈静脉球部进行静脉采样，以避免与脑外灌注血液混合。为了评估这一点的有效性，在猴子身上检查了用同时从颈静脉上球部、下部区域和脑窦获取的血液计算出的值的差异。结果发现，采样位置并未导致显著差异，并且发现PaCO2与CCI之间存在显著相关性。这些发现支持了CCI反映因PaCO2变化而产生的脑血流量这一观点。
