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慢性咳嗽的言语病理学:一种新方法。

Speech pathology for chronic cough: a new approach.

作者信息

Gibson Peter G, Vertigan Anne E

机构信息

Centre for Asthma and Respiratory Diseases, John Hunter Hospital University of Newcastle, Newcastle, NSW, Australia.

出版信息

Pulm Pharmacol Ther. 2009 Apr;22(2):159-62. doi: 10.1016/j.pupt.2008.11.005. Epub 2008 Nov 21.

Abstract

Chronic cough may persist despite systematic evaluation and medical treatment of known associated diseases such as asthma, rhinitis, and gastro-esophageal reflux. These patients have refractory chronic cough and many exhibit laryngeal hypersensitivity that is manifest at both a sensory and motor level. Examples of this are heightened sensitivity of the cough reflex to capsaicin, and laryngeal motor dysfunction with hoarse vocal quality and paradoxical vocal cord movement. Chronic cough that persists despite medical treatment may respond to speech pathology intervention. A multidimensional speech pathology treatment programme was designed based upon methods used to treat hyperfunctional voice disorders and paradoxical vocal fold movement. This included education, vocal hygiene training, cough suppression strategies and psychoeducational counseling. When tested in a single-blind, randomized, placebo-controlled trial involving 87 patients, participants in the treatment group demonstrated a significant reduction in cough, breathing, voice and upper airway symptoms following intervention, as well as improvements in auditory perceptual ratings of voice quality (breathy, rough, strain and glottal fry) and significant improvement in voice acoustic parameters (maximum phonation time, jitter and harmonic-to-noise ratio). Speech pathology intervention can be an effective way to treat refractory chronic cough.

摘要

尽管对哮喘、鼻炎和胃食管反流等已知相关疾病进行了系统评估和药物治疗,慢性咳嗽仍可能持续存在。这些患者患有难治性慢性咳嗽,许多人表现出喉部超敏反应,这在感觉和运动水平上均有体现。例如,咳嗽反射对辣椒素的敏感性增强,以及喉部运动功能障碍,伴有声音嘶哑和矛盾性声带运动。尽管进行了药物治疗,但持续存在的慢性咳嗽可能对言语病理学干预有反应。基于治疗发声功能亢进障碍和矛盾性声带运动所采用的方法,设计了一个多维度的言语病理学治疗方案。这包括教育、发声卫生训练、咳嗽抑制策略和心理教育咨询。在一项涉及87名患者的单盲、随机、安慰剂对照试验中进行测试时,治疗组的参与者在干预后咳嗽、呼吸、声音和上呼吸道症状显著减轻,声音质量的听觉感知评分(呼吸声、粗糙声、紧张声和碎声)有所改善,声音声学参数(最大发声时间、抖动和谐波噪声比)也有显著改善。言语病理学干预可能是治疗难治性慢性咳嗽的有效方法。

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