Attema Arthur E, Brouwer Werner B F
Department of Health Policy and Management, Erasmus University Medical Centre, PO Box 1738, 3000 DR Rotterdam, The Netherlands.
J Health Econ. 2009 Jan;28(1):234-43. doi: 10.1016/j.jhealeco.2008.10.004. Epub 2008 Oct 30.
This paper describes and employs a new method to correct time tradeoff (TTO)-scores for utility of life duration curvature. In contrast to most previous attempts to do so, it uses a risk-free method that corresponds well to the risk-free properties of the TTO-method. In addition, the method is robust to several biases that occur under methods that incorporate risk. Our results show a significant degree of curvature in utility of life duration and therefore a clear bias in TTO-scores. The risk-free method seems to be useful to correct TTO-scores for this influence and leads to significantly higher quality-adjustment factors.
本文描述并采用了一种新方法来校正时间权衡(TTO)分数,以考虑生命持续时间曲率的效用。与以往大多数此类尝试不同,它使用了一种无风险方法,该方法与TTO方法的无风险特性非常契合。此外,该方法对纳入风险的方法中出现的几种偏差具有鲁棒性。我们的结果表明,生命持续时间效用存在显著程度的曲率,因此TTO分数存在明显偏差。无风险方法似乎有助于校正TTO分数的这种影响,并导致显著更高的质量调整因子。