Silverberg K M, Olive D L, Burns W N, Johnson J V, Groff T R, Schenken R S
Department of Obstetrics and Gynecology, University of Texas Health Science Center, San Antonio 78284-7836.
Fertil Steril. 1991 Aug;56(2):296-300. doi: 10.1016/s0015-0282(16)54488-4.
The objectives of this study were: (1) to correlate follicle size by transvaginal sonography with ovulation outcome in cycles of controlled ovarian hyperstimulation with human menopausal gonadotropins; (2) to determine if follicular size on the day of human chorionic gonadotropin (hCG) administration predicts the incidence of ovulation; and, if so, (3) to derive a mathematical model that predicts the number of expected ovulations in any given cycle of controlled ovarian hyperstimulation.
A retrospective analysis.
Forty-nine consecutive patients undergoing 122 cycles of controlled ovarian hyperstimulation were studied in a tertiary care setting.
Follicular size and evidence of ovulation were determined sonographically. The main outcome measure was the rate of ovulation per follicle size.
The percentages of follicles measuring less than or equal to 14 mm, 15 to 16 mm, 17 to 18 mm, 19 to 20 mm, and greater than 20 mm on the day of hCG administration that subsequently ovulated were 0.5%, 37.4%, 72.5%, 81.2%, and 95.5%, respectively.
(1) Follicular size on the day of hCG administration correlates with the incidence of ovulation. (2) The expected number of ovulations in any given controlled ovarian hyperstimulation cycle can be predicted with 95% confidence using the accompanying equation.
本研究的目的是：（1）在使用人绝经期促性腺激素进行控制性卵巢过度刺激的周期中，通过经阴道超声检查将卵泡大小与排卵结果相关联；（2）确定在注射人绒毛膜促性腺激素（hCG）当天的卵泡大小是否能预测排卵发生率；如果可以，（3）推导一个数学模型，以预测在任何给定的控制性卵巢过度刺激周期中预期的排卵数量。
回顾性分析。
在三级医疗机构中对49例连续接受122个周期控制性卵巢过度刺激的患者进行了研究。
通过超声检查确定卵泡大小和排卵证据。主要观察指标是每个卵泡大小的排卵率。
在注射hCG当天，随后排卵的直径小于或等于14mm、15至16mm、17至18mm、19至20mm以及大于20mm的卵泡百分比分别为0.5%、37.4%、72.5%、81.2%和95.5%。
（1）注射hCG当天的卵泡大小与排卵发生率相关。（2）使用附带的方程式，可以95%的置信度预测任何给定的控制性卵巢过度刺激周期中预期的排卵数量。
