Hull M E, Moghissi K S, Magyar D M, Hayes M F, Zador I, Olson J M
Fertil Steril. 1986 Jul;46(1):42-5.
Thirty-eight patients underwent 38 cycles of induction of ovulation using stepwise human menopausal gonadotropin and human chorionic gonadotropin (hCG) administration. Ultrasonography was performed on the day of hCG injection. The mean age +/- standard error of the mean (SEM) of the patients was 32.9 +/- 0.8 years, and the duration of infertility ranged from 1 to 14 years (median, 2.8). Ultrasonographic measurements were obtained of the largest diameter and the volume of the dominant follicles as well as all other follicles in both ovaries. Data were analyzed by Student's t-test, regression analysis, and analysis of variance. The mean +/- SEM diameter of dominant follicles was 1.8 +/- 0.1 cm, and the volume of dominant follicles was 3.5 +/- 0.8 cm. The mean +/- SEM serum estradiol (E2) level before hCG administration was 659 +/- 62 pg/ml. Significant correlations were found between preovulatory serum E2 levels and the total follicular volume of both ovaries (r = 0.41, P less than 0.05) and follicular volume of the ovary containing the dominant follicle (r = 0.42, P less than 0.01). No significant correlation was observed between the diameter of the dominant follicle and serum E2 levels. These results suggest that ultrasound findings reflect growth, whereas serum E2 levels primarily detect functional activity of follicles.
38例患者采用逐步递增人绝经期促性腺激素和人绒毛膜促性腺激素（hCG）进行了38个周期的排卵诱导。在注射hCG当天进行超声检查。患者的平均年龄±平均标准误（SEM）为32.9±0.8岁，不孕持续时间为1至14年（中位数为2.8年）。对双侧卵巢中优势卵泡以及所有其他卵泡的最大直径和体积进行了超声测量。数据采用Student t检验、回归分析和方差分析进行分析。优势卵泡的平均直径±SEM为1.8±0.1 cm，优势卵泡的体积为3.5±0.8 cm。注射hCG前血清雌二醇（E2）的平均水平±SEM为659±62 pg/ml。排卵前血清E2水平与双侧卵巢的卵泡总体积（r = 0.41，P<0.05）以及含有优势卵泡的卵巢的卵泡体积（r = 0.42，P<0.01）之间存在显著相关性。未观察到优势卵泡直径与血清E2水平之间存在显著相关性。这些结果表明，超声检查结果反映卵泡生长，而血清E2水平主要检测卵泡的功能活性。
