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美国毒物控制中心协会国家毒物数据系统(NPDS)2007年度报告:第25次年度报告。

2007 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 25th Annual Report.

作者信息

Bronstein Alvin C, Spyker Daniel A, Cantilena Louis R, Green Jody L, Rumack Barry H, Heard Stuart E

机构信息

American Association of Poison Control Centers, Alexandria, VA 22314, USA.

出版信息

Clin Toxicol (Phila). 2008 Dec;46(10):927-1057. doi: 10.1080/15563650802559632.

Abstract

BACKGROUND

This report is the 25th Annual Report of the American Association of Poison Control Centers (AAPCC; http://www.aapcc.org) National Poison Data System (NPDS). During 2007, 60 of the nation's 61 U.S. Poison Centers upload case data automatically. The median upload time is 14 [5.3, 55] (median [25%, 75%]) min creating a real-time national exposure database and surveillance system.

METHODOLOGY

We analyzed the case data tabulating specific indices from NPDS. The methodology was similar to that of previous years. Where changes were introduced, the differences are identified. Fatalities were reviewed by a team of 29 medical and clinical toxicologists and assigned to 1 of 6 categories according to Relative Contribution to Fatality.

RESULTS

Over 4.2 million calls were captured by NPDS in 2007: 2,482,041 human exposure calls, 1,602,489 information requests, and 131,744 nonhuman exposure calls. Substances involved most frequently in all human exposures were analgesics (12.5% of all exposures). The most common exposures in children less than age 6 were cosmetics/personal care products (10.7% of pediatric exposures). Drug identification requests comprised 66.8% of all information calls. NPDS documented 1,597 human fatalities.

CONCLUSIONS

Poisoning continues to be a significant cause of morbidity and mortality in the United States NPDS represents a valuable national resource to collect and monitor U.S. poisoning exposure cases. It offers one of the few real-time surveillance systems in existence, provides useful data, and is a model for public health surveillance.

摘要

背景

本报告是美国中毒控制中心协会(AAPCC;http://www.aapcc.org)国家中毒数据系统(NPDS)的第25份年度报告。2007年期间,美国61家中毒控制中心中的60家自动上传病例数据。中位上传时间为14[5.3,55](中位数[25%,75%])分钟,从而创建了一个实时的全国暴露数据库和监测系统。

方法

我们分析了从NPDS中提取特定指标的病例数据。方法与前几年类似。如有引入变化之处,则会指明差异。由29名医学和临床毒理学家组成的团队对死亡病例进行了审查,并根据对死亡的相对影响程度将其归入6个类别中的1类。

结果

2007年NPDS记录了超过420万个来电:2482041次人体暴露来电、1602489次信息请求来电以及131744次非人体暴露来电。在所有人体暴露中最常涉及的物质是镇痛药(占所有暴露的12.5%)。6岁以下儿童最常见的暴露是化妆品/个人护理产品(占儿科暴露的10.7%)。药物识别请求占所有信息来电的66.8%。NPDS记录了1597例人体死亡病例。

结论

在美国,中毒仍然是发病和死亡的一个重要原因。NPDS是收集和监测美国中毒暴露病例的宝贵国家资源。它是现存为数不多的实时监测系统之一,提供有用的数据,是公共卫生监测的一个典范。

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