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0至18岁患者急性植物暴露的流行病学及临床特征——一项六年回顾性研究

Epidemiology and Clinical Characteristics of Acute Plant Exposure in Patients Aged between 0 and 18 Years-A Six-Year Retrospective Study.

作者信息

Nițescu Gabriela Viorela, Grama Andreea, Turcu Teodora, Strătulă Andreea, Dragomirescu Ana, Pană Elena Silvia, Baciu Andreea, Baconi Daniela Luiza, Crăciun Maria Dorina, Ulmeanu Coriolan Emil

机构信息

Pediatric Poison Centre, "Grigore Alexandrescu" Clinical Emergency Hospital for Children, 017443 Bucharest, Romania.

Department of Pediatrics, Faculty of Dentistry, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.

出版信息

Children (Basel). 2024 Feb 21;11(3):271. doi: 10.3390/children11030271.

Abstract

BACKGROUND

Exposure to plants accounts for approximately 5% of human poisoning cases reported by poison control centers in North America and Europe. The aim of this study was to investigate acute plant poisoning in patients aged 0-18 years admitted to a Romanian pediatric poison center, focusing on epidemiological and clinical aspects.

METHODS

A retrospective observational study was conducted between 2017 and 2022, analyzing medical records for demographic information, clinical features, biological findings, and outcomes. Statistical analysis was performed using Microsoft Excel.

RESULTS

71 patients (aged 7 months to 16 years) presented with acute plant poisoning. Most cases were unintentional (92.9%), peaking during the autumn season. (18.3%), (9.8%), and (5%) were the most frequently involved plants. Gastrointestinal symptoms, especially vomiting, predominated. The Poisoning Severity Score classified most cases as mild (52.1%), with no severe or fatal cases. The mean length of hospitalization was 1.8 days.

CONCLUSIONS

Unintentional plant exposure, mainly in children under 5 years of age, accounted for more than 90% of cases. Gastrointestinal exposure and symptoms were prevalent, and treatment consisted mainly of symptomatic and supportive measures. Severe and fatal cases were rare, highlighting the generally favorable outcome and low incidence of severe poisoning in the pediatric population.

摘要

背景

在北美和欧洲的中毒控制中心报告的人类中毒病例中,接触植物导致的中毒约占5%。本研究的目的是调查罗马尼亚一家儿科中毒中心收治的0至18岁患者的急性植物中毒情况,重点关注流行病学和临床方面。

方法

在2017年至2022年期间进行了一项回顾性观察研究,分析病历中的人口统计学信息、临床特征、生物学检查结果和结局。使用Microsoft Excel进行统计分析。

结果

71例患者(年龄7个月至16岁)出现急性植物中毒。大多数病例为意外中毒(92.9%),秋季中毒病例数达到峰值。(18.3%)、(9.8%)和(5%)是最常涉及的植物。胃肠道症状,尤其是呕吐,最为常见。中毒严重程度评分将大多数病例归类为轻度(52.1%),无严重或致命病例。平均住院时间为1.8天。

结论

意外接触植物主要发生在5岁以下儿童中,占病例数的90%以上。胃肠道接触和症状很普遍,治疗主要包括对症和支持措施。严重和致命病例很少见,这突出表明儿科人群中中毒的总体预后良好且严重中毒发生率较低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1810/10969538/e2590210ae47/children-11-00271-g001.jpg

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