Haldre Kai, Rahu Kaja, Karro Helle, Rahu Mati
Department of Obstetrics and Gynaecology, University of Tartu, Tartu, Estonia.
J Matern Fetal Neonatal Med. 2008 Dec;21(12):884-8. doi: 10.1080/14767050802320324.
To estimate the risk of complications of the third stage of labour needing manual revision of uterine cavity or curettage in deliveries following one or multiple induced abortions in nulliparous women who had singleton live births in Estonia in 1994-2002.
Registry study using the data from the Estonian medical birth registry: 32,652 women had not had any abortions, 7,333 women had had one and 2,383 women had had two or more surgically induced abortions before their first delivery. Multiple logistic regression analysis was performed to estimate crude odds ratios (OR), adjusted ORs and their 95% confidence intervals, with women having had no abortions as the reference group. Adjustment was made for maternal age, sex and weight of infant, labour induction/augmentation.
In the single abortion group, the crude OR was 1.25 (95% confidence intervals (CI) 1.12-1.40), the adjusted OR was 1.23 (95% CI 1.10-1.38); in the multiple abortion group the crude OR was 1.28 (95% CI 1.06-1.53), the adjusted OR was 1.24 (95% CI 1.03-1.49).
Our findings suggest a positive association between one or more first trimester abortion(s) and the risk of complications in the third stage of labour in subsequent singleton delivery.
评估1994 - 2002年在爱沙尼亚单胎活产的未生育妇女中，经历一次或多次人工流产后分娩时发生需要手动清宫或刮宫的第三产程并发症的风险。
采用爱沙尼亚医学出生登记处的数据进行登记研究：32652名妇女未进行过任何人工流产，7333名妇女进行过一次人工流产，2383名妇女在首次分娩前进行过两次或更多次人工流产。以未进行过人工流产的妇女为参照组，进行多因素logistic回归分析以估计粗比值比（OR）、调整后的OR及其95%置信区间。对产妇年龄、婴儿性别和体重、引产/催产进行了校正。
在单次人工流产组中，粗OR为1.25（95%置信区间（CI）1.12 - 1.40），调整后的OR为1.23（95%CI 1.10 - 1.38）；在多次人工流产组中，粗OR为1.28（95%CI 1.06 - 1.53），调整后的OR为1.24（95%CI 1.03 - 1.49）。
我们的研究结果表明，首次孕期进行一次或多次人工流产与随后单胎分娩第三产程并发症风险之间存在正相关。
