Taylor V M, Kramer M D, Vaughan T L, Peacock S
Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington.
Obstet Gynecol. 1993 Jul;82(1):88-91.
To evaluate the impact of induced abortion and spontaneous abortion on the occurrence of placenta previa in later pregnancies.
A population-based, case-control study was conducted using 1984-1987 Washington state birth certificate data. The study population included 486 white women with a pregnancy complicated by placenta previa and 1598 randomly selected controls without placenta previa. Unconditional logistic regression was used to estimate odds ratios and 95% confidence intervals (CIs).
After adjustment for confounding variables, the odds ratio in association with one or more induced abortions was 1.28 (95% CI 1.00-1.63). For one or more spontaneous abortions, the odds ratio was 1.30 (95% CI 1.01-1.66).
Women who report one or more induced or spontaneous abortions are 30% more likely to have a subsequent pregnancy complicated by placenta previa than women without such a history. The results should not be generalized to areas where suction curettage is not the preferred method of induced abortion.
评估人工流产和自然流产对后续妊娠中前置胎盘发生情况的影响。
利用1984 - 1987年华盛顿州出生证明数据进行一项基于人群的病例对照研究。研究人群包括486例妊娠合并前置胎盘的白人女性以及1598例随机选取的无前置胎盘的对照。采用非条件逻辑回归来估计比值比及95%置信区间(CI)。
在对混杂变量进行调整后,与一次或多次人工流产相关的比值比为1.28(95%CI 1.00 - 1.63)。对于一次或多次自然流产,比值比为1.30(95%CI 1.01 - 1.66)。
报告有一次或多次人工流产或自然流产的女性,其后续妊娠合并前置胎盘的可能性比无此类病史的女性高30%。这些结果不应推广至负压吸宫术并非人工流产首选方法的地区。