Sevast'ianova E V, Petrova L V
Probl Tuberk Bolezn Legk. 2008(9):13-6.
Drug resistance (DR) in Mycobacterium tuberculosis (MBT) has been monitored in the Republic of Mariy El. It has been established that there is a considerable prevalence of drug-resistance strains even among new cases. There is a gradual rise in the level of MBT DR, including multiple DR (MDR). In 2000 and 2006, the rates of primary MBT DR were 26.7 and 31.5% (including those of MDR were 10.2 and 13%), respectively. The proportion of strains resistant to 4 major antituberculous drugs (I, R, S, E) of the number of DR cultures increased from 19% in 2003 to 35% in 2005, which suggests the situation of high strain with the prevalence of DR tuberculosis in the Republic of Mariy El.
马里埃尔共和国一直在监测结核分枝杆菌（MBT）的耐药性。已确定即使在新发病例中，耐药菌株的患病率也相当高。MBT耐药水平，包括多重耐药（MDR），呈逐渐上升趋势。2000年和2006年，原发性MBT耐药率分别为26.7%和31.5%（其中MDR分别为10.2%和13%）。对4种主要抗结核药物（异烟肼、利福平、链霉素、乙胺丁醇）耐药的菌株在耐药培养菌株中的比例从2003年的19%增至2005年的35%，这表明马里埃尔共和国存在耐多药结核病高发的情况。
