Trabelsi Amel, Stita Wided, Yacoubi Mohamed Tahar, Rammeh Soumaya, Hmissa Sihem, Korbi Sadok
Department of Pathology, CHU Farhat Hached, Sousse, Tunisia.
Can Urol Assoc J. 2008 Dec;2(6):635-6. doi: 10.5489/cuaj.984.
We report a case of mucinous tubular and spindle cell carcinoma in a 66-year-old woman. The tumour, located on the left kidney, was well circumscribed. Microscopically, the tumour was composed of cuboidal cells arranged in tubules and making abrupt transitions to spindle cell morphology in a myxoid stroma. Tumour cells were strongly positive for cytokeratin 7 and epithelial membrane antigen. Because of the favourable prognosis with this type of tumour, mucinous tubular and spindle cell carcinoma must be differentiated from papillary renal cell carcinoma, especially that with sarcomatoid change. No tumour recurrence or metastasis were reported with a follow-up of 23 months.
我们报告一例66岁女性的黏液性小管状和梭形细胞癌。肿瘤位于左肾，边界清晰。显微镜下，肿瘤由排列成小管状的立方细胞组成，并在黏液样间质中突然转变为梭形细胞形态。肿瘤细胞细胞角蛋白7和上皮膜抗原呈强阳性。由于这类肿瘤预后良好，黏液性小管状和梭形细胞癌必须与乳头状肾细胞癌相鉴别，尤其是伴有肉瘤样改变的乳头状肾细胞癌。随访23个月，未报告肿瘤复发或转移。
