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食管裂孔闭合术假体加固后的网片并发症:28例病例系列

Mesh complications after prosthetic reinforcement of hiatal closure: a 28-case series.

作者信息

Stadlhuber Rudolf J, Sherif Amr El, Mittal Sumeet K, Fitzgibbons Robert J, Michael Brunt L, Hunter John G, Demeester Tom R, Swanstrom Lee L, Daniel Smith C, Filipi Charles J

机构信息

Department of Surgery, Creighton University School of Medicine, 601 N 30th Street, Suite 3740, Omaha, NE 68131-2197, USA.

出版信息

Surg Endosc. 2009 Jun;23(6):1219-26. doi: 10.1007/s00464-008-0205-5. Epub 2008 Dec 6.

Abstract

BACKGROUND

Primary laparoscopic hiatal hernia repair is associated with up to a 42% recurrence rate. This has lead to the use of mesh for crural repair, which has resulted in an improved recurrence rate (0-24%). However, mesh complications have been observed.

METHODS

We compiled two cases, and our senior author contacted other experienced esophageal surgeons who provided 26 additional cases with mesh-related complications. Care was taken to retrieve technical operative details concerning mesh size and shape and implantation technique used.

RESULTS

Twenty-six patients underwent laparoscopic and two patients open surgery for large hiatal hernia (n = 28). Twenty-five patients had a concomitant Nissen fundoplication, two a Toupet fundoplication, and one a Watson fundoplication. Mesh types placed were polypropylene (n = 8), polytetrafluoroethylene (PTFE) (n = 12), biological mesh (n = 7), and dual mesh (n = 1). Presenting symptoms associated with mesh complications were dysphagia (n = 22), heartburn (n = 10), chest pain (n = 14), fever (n = 1), epigastric pain (n = 2), and weight loss (n = 4). Main reoperative findings were intraluminal mesh erosion (n = 17), esophageal stenosis (n = 6), and dense fibrosis (n = 5). Six patients required esophagectomy, two patients had partial gastrectomy, and 1 patient had total gastrectomy. Five patients did not require surgery. In this group one patient had mesh removal by endoscopy. There was no immediate postoperative mortality, however one patient has severe gastroparesis and five patients are dependent on tube feeding. Two patients died 3 months postoperatively of unknown cause. There is no apparent relationship between mesh type and configuration with the complications encountered.

CONCLUSION

Complications related to synthetic mesh placement at the esophageal hiatus are more common than previously reported. Multicenter prospective studies are needed to determine the best method and type of mesh for implantation.

摘要

背景

原发性腹腔镜食管裂孔疝修补术的复发率高达42%。这导致了使用补片进行膈肌脚修补,从而使复发率得到改善(0 - 24%)。然而,已观察到补片相关并发症。

方法

我们收集了2例病例,我们的资深作者联系了其他经验丰富的食管外科医生,他们又提供了另外26例有补片相关并发症的病例。我们仔细获取了有关补片大小、形状及所使用的植入技术的手术操作细节。

结果

28例大型食管裂孔疝患者中,26例行腹腔镜手术,2例行开放手术。25例同时行nissen胃底折叠术,2例行Toupet胃底折叠术,1例行Watson胃底折叠术。所放置的补片类型为聚丙烯补片(8例)、聚四氟乙烯(PTFE)补片(12例)、生物补片(7例)和双层补片(1例)。与补片并发症相关的主要症状为吞咽困难(22例)、烧心(10例)、胸痛(14例)、发热(1例)、上腹部疼痛(2例)和体重减轻(4例)。再次手术的主要发现为腔内补片侵蚀(17例)、食管狭窄(6例)和致密纤维化(5例)。6例患者需要行食管切除术,2例患者行部分胃切除术,1例患者行全胃切除术。5例患者不需要手术。在该组中,1例患者通过内镜取出补片。术后无即刻死亡病例,然而1例患者有严重胃轻瘫,5例患者依赖鼻饲。2例患者术后3个月不明原因死亡。补片类型和构型与所遇到的并发症之间无明显关系。

结论

食管裂孔处放置合成补片相关的并发症比先前报道的更为常见。需要进行多中心前瞻性研究以确定最佳的补片植入方法和类型。

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