Balasubramaniam Ramesh, Sollecito Thomas P, Stoopler Eric T
Department of Oral Medicine, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, USA.
Spec Care Dentist. 2008 Nov-Dec;28(6):243-53. doi: 10.1111/j.1754-4505.2008.00047.x.
Muscular dystrophies (MD) are a heterogeneous group of inherited neuromuscular disorders characterized by muscle necrosis and progressive muscle weakness. It is important for oral healthcare providers to be familiar with MD as special considerations are necessary to provide appropriate and safe dental care for these medically complex patients. This article briefly reviews the more common types of MD, namely, Duchenne MD, Becker MD, Emery-Dreifuss MD, facioscapulo-humeral MD, limb-girdle MD, oculopharyngeal MD, and myotonic dystrophy. Aspects of their epidemiology, pathophysiology, clinical presentation, diagnosis, and medical management as well as oral health considerations are discussed.
肌肉萎缩症（MD）是一组遗传性神经肌肉疾病的统称，其特征为肌肉坏死和进行性肌无力。对于口腔医疗服务提供者而言，熟悉肌肉萎缩症很重要，因为对于这些患有复杂疾病的患者，需要特别考虑以提供恰当且安全的牙科护理。本文简要回顾了肌肉萎缩症的几种较常见类型，即杜兴氏肌肉萎缩症、贝克氏肌肉萎缩症、埃默里-德赖富斯肌肉萎缩症、面肩肱型肌肉萎缩症、肢带型肌肉萎缩症、眼咽型肌肉萎缩症以及强直性肌营养不良症。文中讨论了这些疾病的流行病学、病理生理学、临床表现、诊断、药物治疗以及口腔健康方面的考量。
