Carelsen Bart, Jonges Remmet, Strackee Simon D, Maas Mario, van Kemenade Patricia, Grimbergen Cornelis A, van Herk Marcel, Streekstra Geert J
Department of Medical Physics, Academic Medical Center, 1100 DD Amsterdam, The Netherlands.
IEEE Trans Biomed Eng. 2009 Apr;56(4):1236-44. doi: 10.1109/TBME.2008.2009069. Epub 2008 Dec 9.
We present a method for measurement dynamic in vivo carpal motion patterns. The method consists of a 4-D rotational X-ray (RX) with improved image quality and image processing for accurate detection in vivo wrist motion measurements. Dynamic 3-D imaging yields a number of volume reconstructions of the wrist at different phases of its cyclic motion. Next, the carpal reconstructions are registered to their static acquired and segmented counterpart in all phases. With this information, the relation between the applied motion and carpal kinematic behavior is acquired, i.e., the motion patterns. We investigated the precision of the image acquisition and processing and tested it on three healthy subjects. The precision of the image acquisition and image processing is in the range of submillimeters and subdegrees, respectively, which is better than existing systems and sufficient for clinical investigations. Reproducibility measurements show some more deviation ( > 1 degrees). This method was tested on four human volunteers and agrees for the greater part with previously done invasive and nondynamic measurements. In vivo motion pattern measurement with 4-D-RX imaging and processing is accurate and noninvasive. The motion patterns can reveal disorders that could not have been detected in either video fluoroscopy, computed tomography, or MRI.
我们提出了一种测量活体腕部动态运动模式的方法。该方法包括具有改进图像质量的四维旋转X射线（RX）以及用于准确检测活体腕部运动测量的图像处理。动态三维成像可在腕部循环运动的不同阶段生成多个腕部的体积重建图像。接下来，将腕骨重建图像与所有阶段中获取的静态图像及其分割后的对应图像进行配准。利用这些信息，可获取所施加运动与腕骨运动行为之间的关系，即运动模式。我们研究了图像采集和处理的精度，并在三名健康受试者身上进行了测试。图像采集和图像处理的精度分别在亚毫米和亚度范围内，优于现有系统，足以用于临床研究。重复性测量显示存在一些更大的偏差（>1度）。该方法在四名人类志愿者身上进行了测试，在很大程度上与先前进行的侵入性和非动态测量结果一致。利用四维RX成像和处理进行活体运动模式测量准确且无创。这些运动模式可以揭示在视频荧光透视、计算机断层扫描或磁共振成像中无法检测到的疾病。
