司帕沙星在肺结核联合治疗中的应用
[Sparfloxacin in combined therapy for pulmonary tuberculosis].
作者信息
Sokolova G B, Khaĭmenova T Iu, Lazareva Ia V, Khaĭmenov A Ia
出版信息
Antibiot Khimioter. 2008;53(5-6):21-7.
PMID:19069178
Abstract
Efficacy and safety of the difluoroquinolone sparfloxacine used in combined therapy for drug-succeptible and drug-resistant pulmonary tuberculosis were studied. Clinical trials enrolled 60 patients with severe pulmonary tuberculosis. The most effective combinations of sparfloxacine and other antituberculous drugs were determined. Data on satisfactory tolerability of sparfloxacine used in various combinations of the main and reserve agents are presented.
摘要
研究了二氟喹诺酮类药物司帕沙星在联合治疗药物敏感和耐药性肺结核中的疗效及安全性。临床试验纳入了60例重症肺结核患者。确定了司帕沙星与其他抗结核药物的最有效联合用药方案。给出了司帕沙星在主要药物和储备药物的各种联合用药中耐受性良好的数据。
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