Villegas Víctor M, Díaz Lilliam, Izquierdo Natalio J
University of Puerto Rico, Medical Sciences Campus, Rio Piedras, Puerto Rico.
P R Health Sci J. 2008 Dec;27(4):348-9.
To report a patient with glaucoma who developed recurrent herpetic keratitis while using two different prostaglandin analogue ophthalmic solutions.
A 72 year-old male patient with primary open angle glaucoma and a history of herpetic keratitis in the left eye experienced recurrent herpetic keratitis in the left eye after treatment with latanoprost ophthalmic solution. Herpetic flares were controlled after discontinuation of latanoprost. Adding travoprost ophthalmic solution 0.004% to his glaucoma therapy was also associated with a recurrence of herpetic keratitis.
To our knowledge, this is the first case in which travoprost has been associated to recurrent herpetic keratitis. Further, this is the first report in which a patient has a recurrence of herpetic keratitis associated to two different prostaglandin analogues. These findings suggest that patients with recurrent herpetic keratitis associated to a prostaglandin analogue might be predisposed to a flare-up with other prostaglandin analogues.
报告一名青光眼患者,在使用两种不同的前列腺素类似物滴眼液时发生复发性疱疹性角膜炎。
一名72岁男性原发性开角型青光眼患者,左眼有疱疹性角膜炎病史,在用拉坦前列素滴眼液治疗后左眼发生复发性疱疹性角膜炎。停用拉坦前列素后疱疹性炎症得到控制。在其青光眼治疗中加用0.004%曲伏前列素滴眼液也与疱疹性角膜炎复发有关。
据我们所知,这是首例曲伏前列素与复发性疱疹性角膜炎相关的病例。此外,这是首例患者使用两种不同前列腺素类似物均出现疱疹性角膜炎复发的报告。这些发现提示,与一种前列腺素类似物相关的复发性疱疹性角膜炎患者可能易因其他前列腺素类似物而出现病情复发。