Corti Marcelo, Villafañe Maria Florencia, Negroni Ricardo, Arechavala Alicia, Maiolo Elena
Division of HIV/AIDS Disease, F. J. Muñiz Hospital, Buenos Aires, Argentina.
Rev Iberoam Micol. 2008 Dec 31;25(4):211-4. doi: 10.1016/s1130-1406(08)70051-2.
Cryptococcosis is an opportunistic fungal infection caused by Cryptococcus neoformans. Generally, the disease affects the central nervous system, especially in patients with human immunodeficiency virus infection. Central nervous system involvement can be either meningeal or parenchymal. As the infection spreads along the Virchow-Robin spaces these structures may dilate with the mucoid and gelatinous material produced by the organism's capsule. The lesions associated with the dilatation of Virchow-Robin spaces are referred to as gelatinous pseudocysts. Bigger lesions are known as cryptococcomas. In this article we describe five patients with neurocryptococcosis associated with AIDS and parenchymal lesions compatible with gelatinous pseudocysts and cryptococcomas.
隐球菌病是由新型隐球菌引起的一种机会性真菌感染。一般来说,该疾病会影响中枢神经系统,尤其是在人类免疫缺陷病毒感染患者中。中枢神经系统受累可为脑膜型或实质型。随着感染沿血管周围间隙扩散,这些结构可能会因病原体荚膜产生的黏液样和胶样物质而扩张。与血管周围间隙扩张相关的病变称为胶样假囊肿。较大的病变称为隐球菌瘤。在本文中,我们描述了五例与艾滋病相关的神经隐球菌病患者,其具有与胶样假囊肿和隐球菌瘤相符的实质病变。