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亚急性下肢缺血的血管内治疗

Endovascular management of subacute lower extremity ischemia.

作者信息

Dosluoglu Hasan H, Harris Linda M

机构信息

Division of Vascular Surgery, Department of Surgery, VA Western NY Healthcare System, Buffalo, NY 14215, USA.

出版信息

Semin Vasc Surg. 2008 Dec;21(4):167-79. doi: 10.1053/j.semvascsurg.2008.11.002.

Abstract

Patients presenting with >14 days lower extremity ischemia are usually considered as chronic; however, patients with subacute (>14 days and <3 months) and chronic (>3 months) occlusions often have organizing thrombus. This is not considered in current recommendations for the treatment of nonacute leg ischemia and, with the increased use of endovascular interventions, more complex lesions with long occlusions are treated percutaneously. Thrombolysis alone has been reported to successfully decrease this clot load in a significant proportion of patients with subacute occlusions, and percutaneous thrombectomy devices were suggested as a means to decrease the hemorrhagic complications associated with thrombolysis. However, distal embolization remains a problem, which these interventions are intended to prevent. In this article, we aim to review the current literature on the endovascular treatment of patients with subacute arterial occlusions, and review our experience.

摘要

出现下肢缺血超过14天的患者通常被视为慢性患者;然而,亚急性(>14天且<3个月)和慢性(>3个月)闭塞的患者常有正在机化的血栓。目前关于非急性腿部缺血治疗的建议未考虑到这一点,并且随着血管内介入治疗的使用增加,更长闭塞的更复杂病变也通过经皮方式进行治疗。据报道,单独溶栓可在相当一部分亚急性闭塞患者中成功减少血栓负荷,并且有人建议使用经皮血栓切除术装置作为减少与溶栓相关的出血并发症的一种手段。然而,远端栓塞仍然是一个问题,而这些干预措施旨在预防这一问题。在本文中,我们旨在回顾关于亚急性动脉闭塞患者血管内治疗的当前文献,并回顾我们的经验。

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